Evidence map›Paper›PMID 39190452›Full record

ArticleeLife2024

Hosts manipulate lifestyle switch and pathogenicity heterogeneity of opportunistic pathogens in the single-cell resolution.

Ziguang Wang, Shuai Li, Sheng Zhang, Tianyu Zhang, Yujie Wu, Anqi Liu, Kui Wang, Xiaowen Ji, Haiqun Cao, Yinglao Zhang and 4 more

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Comparative genomic analysis ofMicrobiology spectrum · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ziguang Wang *School of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.
Shuai Li *Bioinformatics Center, College of Biology, Hunan University, Changsha, China.
Sheng ZhangSchool of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.
Tianyu ZhangLiangzhu Laboratory, Zhejiang University, Hangzhou, China.
Yujie WuSchool of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.
Anqi LiuSchool of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.
Kui WangSchool of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.
Xiaowen JiSchool of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.
Haiqun CaoSchool of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.
Yinglao ZhangSchool of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.
Eng King TanDepartment of Neurology, National Neuroscience Institute, Singapore General Hospital Campus, Singapore, Singapore.
Yongcheng WangLiangzhu Laboratory, Zhejiang University, Hangzhou, China.
Yirong WangBioinformatics Center, College of Biology, Hunan University, Changsha, China.ORCID https://orcid.org/0000-0002-1995-2728
Wei LiuSchool of Plant Protection; Anhui Province Key Laboratory of Crop Integrated Pest Management; Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization, Anhui Agricultural University, Hefei, China.ORCID https://orcid.org/0000-0002-1059-6261

Funding

Anhui Province Key Laboratory of Resource Insect Biology and Innovative Utilization FKLRIB202401Fundamental Research Funds for the Central Universities of China 531118010546Ministry of Science and Technology of the People's Republic of China 2022YFE0132000National Natural Science Foundation of China 31501175National Natural Science Foundation of China 32470044Natural Science Foundation of Anhui Province 2308085MC74Natural Science Foundation of Hunan Province 2022JJ40048Talents in Anhui Agricultural University RC342201
6 · The paper itself

Abstract

Host-microbe interactions are virtually bidirectional, but how the host affects their microbiome is poorly understood. Here, we report that the host is a critical modulator to regulate the lifestyle switch and pathogenicity heterogeneity of the opportunistic pathogens

Indexed as

Drosophila melanogasterHost-Pathogen InteractionsLarvaSerratia marcescensAnimalsDrosophilaSingle-Cell AnalysisSymbiosisVirulencebacterial single-cell RNA-seqD. melanogasterhost-microbe interactionsinfectious diseaselifestyle switchmicrobiologypathogenicity heterogeneitySerratia marcescens

Identifiers

PMID39190452
PMCPMC11349298

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.