ArticleBrain, behavior, and immunity2024
CD8
Abstract read
In one paragraph
Article in Brain, behavior, and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Targeting CXCL8 in post-traumatic stress disorder and Alzheimer's disease: insights from cross-disorder molecular analysis.Annals of medicine · 2026Article
- Neural network-enhanced investigation of ferroptosis and druggability in early-onset alzheimer's disease.Metabolic brain disease · 2026Article
- Recent advances in Alzheimer's disease: From molecular mechanisms to therapeutic strategies.Cell · 2026Review
- Senescence of T cells and organ aging.Inflammation and regeneration · 2026Review
- Indigenous gut microbes modulate neural cell state and neurodegenerative disease susceptibility.Cell systems · 2026Article
- Association between Alzheimer's disease and MHC-I antigen processing and presentation pathway: a narrative review.Frontiers in immunology · 2026Review
- Adaptive Immunity and Alzheimer's Disease: Dual Roles in Neurodegeneration and Neuroprotection with Therapeutic Implications.Biomolecules & therapeutics · 2026Review
- Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer's Disease mouse model.Biology of sex differences · 2025Article
- Stage-specific roles of clonally expanded CD8Nature communications · 2025Article
- A distinct population of CD8Nature aging · 2025Article
- Genotype and microbiome shape immunity in a sex-specific manner in mouse models of Alzheimer's disease.Brain, behavior, and immunity · 2025Article
- Physiological microbial exposure normalizes memory T cell surveillance of the brain and modifies host seizure outcomes.Nature immunology · 2025Article
- Antigen-Specifically Activated CD8+ and Double-Negative T Cells Accumulate in the Brain of Alzheimer's Disease Mice.Aging and disease · 2025Article
- Article
- Peripheral and central neuroimmune mechanisms in Alzheimer's disease pathogenesis.Molecular neurodegeneration · 2025Review
- Novel insights from comprehensive analysis: The role of cuproptosis and peripheral immune infiltration in Alzheimer's disease.PloS one · 2025Article
- Approaches for studying neuroimmune interactions in Alzheimer's disease.Trends in immunology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Xin WangImmunoregulation Section, Laboratory of Molecular Biology and Immunolgy, USA.
Britney CampbellImmunoregulation Section, Laboratory of Molecular Biology and Immunolgy, USA.
Monica BodogaiImmunoregulation Section, Laboratory of Molecular Biology and Immunolgy, USA.
Ross A McDevittMouse Phenotyping Unit, Comparative Medicine Section, National Institute on Aging, Baltimore, MD, USA.
Anton PatrikeevDepartment of Psychiatry, University of Massachusetts Medical School, Worcester, MA, USA.
Fedor GusevDepartment of Psychiatry, University of Massachusetts Medical School, Worcester, MA, USA.
Emeline RagonnaudImmunoregulation Section, Laboratory of Molecular Biology and Immunolgy, USA.
Konda KumaraswamiImmunoregulation Section, Laboratory of Molecular Biology and Immunolgy, USA.
Sophie ShirenovaThe Leslie and Susan Gonda Multidisciplinary Brain Research Center, Israel; The Mina and Everard Goodman Faculty of Life Sciences, Israel; The Paul Feder Laboratory on Alzheimer's Disease Research, Bar-Ilan University, Ramat Gan, Israel.
Karin VardyThe Leslie and Susan Gonda Multidisciplinary Brain Research Center, Israel; The Mina and Everard Goodman Faculty of Life Sciences, Israel; The Paul Feder Laboratory on Alzheimer's Disease Research, Bar-Ilan University, Ramat Gan, Israel.
Mohamed-Gabriel AlamehInstitute of RNA Innovation, University of Pennsylvania, Philadelphia, PA, USA.
Drew WeissmanInstitute of RNA Innovation, University of Pennsylvania, Philadelphia, PA, USA.
Hellen Ishikawa-AnkerholdDepartment of Medicine I, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany; Institute of Surgical Research at the Walter Brendel Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany.
Eitan OkunThe Leslie and Susan Gonda Multidisciplinary Brain Research Center, Israel; The Mina and Everard Goodman Faculty of Life Sciences, Israel; The Paul Feder Laboratory on Alzheimer's Disease Research, Bar-Ilan University, Ramat Gan, Israel.
Evgeny RogaevDepartment of Psychiatry, University of Massachusetts Medical School, Worcester, MA, USA.
Arya BiragynImmunoregulation Section, Laboratory of Molecular Biology and Immunolgy, USA. Electronic address: biragyna@mail.nih.gov.
Funding
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8MMulti-omic network-directed proteoform discovery, dissection and functional validation to prioritize novel AD therapeutic targetsU01AG061356 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BENNETT, DAVID ALAN, DE JAGER, PHILIP L · 2018 to 2022
$13.7MPathway discovery, validation and compound identification for Alzheimer's disease - SupplementU01AG046152 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BENNETT, DAVID ALAN, DE JAGER, PHILIP L · 2013 to 2017
$13.6MAlzheimer variants: Propagation of shared functional changes across cellular networksU01AG072572 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DE JAGER, PHILIP L, ST GEORGE-HYSLOP, PETER HENRY · 2021 to 2025
$8.5MDeconstructing and modeling the single cell architecture of the Alzheimer brainRF1AG057473 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BENNETT, DAVID ALAN, DE JAGER, PHILIP L · 2017 to 2018
$4.0MElucidating changes in astrocyte subpopulations associated with resistance to Alzheimers Disease pathology in multi-ethnic cohortsR01AG066831 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MENON, VILAS · 2020 to 2024
$3.3MB cells promote Alzheimers disease via cytolytic CD8+ T cellsZIAAG000582 · NIA · NATIONAL INSTITUTE ON AGING · PI BIRAGYN, ARYA · 2022 to 2025
$1.0MIntramural NIH HHS ZIA AG000582NIA NIH HHS R01 AG066831NIA NIH HHS RF1 AG057473NIA NIH HHS U01 AG046152NIA NIH HHS U01 AG061356NIA NIH HHS U01 AG072572NIA NIH HHS U24 AG021886
Abstract
Alzheimer's disease (AD) is linked to toxic Aβ plaques in the brain and activation of innate responses. Recent findings however suggest that the disease may also depend on the adaptive immunity, as B cells exacerbate and CD8
Indexed as
Alzheimer DiseaseAmyloidosisBrainCD8-Positive T-LymphocytesDisease Models, AnimalMicrogliaAdaptive ImmunityAmyloid beta-PeptidesAnimalsB-LymphocytesCytokinesFemaleHumansMaleMiceMice, Inbred C57BLAmyloid beta-PeptidesCytokinesAlzheimer’s diseaseAmyloidosisAβ responseB cellsCD8(+) T cells
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.