Evidence mapPaperPMID 39193116Full record

ReviewMethodist DeBakey cardiovascular journal2024

Role of Imaging and Biomarkers in Identifying, Monitoring, and Promoting Myocardial Recovery.

Evelyne Meekers, Matthias Dupont

Abstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Evelyne MeekersZiekenhuis Oost-Limburg A.V., Genk, Belgium.ORCID https://orcid.org/0000-0002-0204-0132
Matthias DupontZiekenhuis Oost-Limburg A.V., Genk, Belgium.ORCID https://orcid.org/0000-0002-0802-9508

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reverse remodeling, the overarching concept behind myocardial recovery, describes the process in which the maladaptive cardiac structural and functional alterations are reversed by removing the underlying etiology or by therapy. This review addresses different imaging modalities and biomarkers as possible predictors for reverse remodeling in patients with chronic heart failure. Although echocardiography remains the imaging modality of choice in daily practice, the presence and amount of fibrosis on cardiac magnetic resonance is a better predictor and inversely correlated with the likelihood for reverse remodeling. A decrease in NT-proBNP levels and serum soluble ST3 during follow-up is associated with better clinical and structural outcomes. The role of troponins and galectine-3 is less clear. There is a promising role for microRNAs in the future, although more research is necessary. Accurate predictors of reverse remodeling could help identify patients with an increased likelihood for reverse remodeling and, in turn, improve patient-tailored medicine.

Indexed as

BiomarkersHeart FailurePredictive Value of TestsRecovery of FunctionVentricular Function, LeftVentricular RemodelingChronic DiseaseEchocardiographyFibrosisHumansMagnetic Resonance ImagingMyocardiumTreatment OutcomeBiomarkersbiomarkerscardiac magnetic resonanceechocardiographyheart failureimagingmyocardial recoveryreverse remodeling

Identifiers

PMID39193116
PMCPMC11348843

What Socratic holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.