Evidence map›Paper›PMID 39193642›Full record

ArticleJournal of the Royal Society, Interface2024

Neuronal network dynamics in the posterodorsal amygdala: shaping reproductive hormone pulsatility.

Kateryna Nechyporenko, Margaritis Voliotis, Xiao Feng Li, Owen Hollings, Deyana Ivanova, Jamie J Walker, Kevin T O'Byrne, Krasimira Tsaneva-Atanasova

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kateryna NechyporenkoDepartment of Mathematics and Statistics, University of Exeter, Stocker Road, Exeter EX4 4PY, UK.ORCID 0000-0003-1933-9314
Margaritis VoliotisDepartment of Mathematics and Statistics, University of Exeter, Stocker Road, Exeter EX4 4PY, UK.
Xiao Feng LiDepartment of Women and Children's Health, School of Life Course and Population Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.
Owen HollingsDepartment of Women and Children's Health, School of Life Course and Population Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.
Deyana IvanovaDivision of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Jamie J WalkerDepartment of Mathematics and Statistics, University of Exeter, Stocker Road, Exeter EX4 4PY, UK.
Kevin T O'ByrneDepartment of Women and Children's Health, School of Life Course and Population Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.
Krasimira Tsaneva-AtanasovaDepartment of Mathematics and Statistics, University of Exeter, Stocker Road, Exeter EX4 4PY, UK.

Funding

Biotechnology and Biological Sciences Research CouncilEngineering and Physical Sciences Research CouncilMedical Research Council
6 · The paper itself

Abstract

Normal reproductive function and fertility rely on the rhythmic secretion of gonadotropin-releasing hormone (GnRH), which is driven by the hypothalamic GnRH pulse generator. A key regulator of the GnRH pulse generator is the posterodorsal subnucleus of the medial amygdala (MePD), a brain region that is involved in processing external environmental cues, including the effect of stress. However, the neuronal pathways enabling the dynamic, stress-triggered modulation of GnRH secretion remain largely unknown. Here, we employ

Indexed as

Gonadotropin-Releasing HormoneAmygdalaAnimalsGABAergic NeuronsMiceModels, NeurologicalNerve NetNeuronsGonadotropin-Releasing Hormonebifurcation analysiscomputational health modellingreproductive health and functionstress-mediated neuromodulationssystem dynamics in health innovations

Identifiers

PMID39193642
PMCPMC11350435

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.