Evidence map›Paper›PMID 39195542›Full record

ArticleMetabolites2024

Fufang Muji Granules Ameliorate Liver Fibrosis by Reducing Oxidative Stress and Inflammation, Inhibiting Apoptosis, and Modulating Overall Metabolism.

Lei Men, Zhihong Gu, Enhua Wang, Jiwen Li, Zhongyu Li, Keke Li, Chunbin Li, Xiaojie Gong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei MenDepartment of Biological Engineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.ORCID 0000-0002-0557-659X
Zhihong GuDepartment of Biological Engineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Enhua WangDepartment of Biological Engineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Jiwen LiDepartment of Biological Engineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Zhongyu LiDepartment of Biological Engineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Keke LiDepartment of Biological Engineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Chunbin LiDepartment of Biological Engineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Xiaojie GongDepartment of Biological Engineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.ORCID 0000-0001-8811-4333

Funding

Fundamental Research Funds for the Central Universities 2023-SWGC-0101High-level Talent Innovation Support Program of Dalian 2021RD10Joint Program (Applied Basic Research Project) of Liaoning Provincial Science and Technology Program 2023JH2/101700074National Natural Science Foundation of China 82104532 and 82173913
6 · The paper itself

Abstract

Fufang Muji granules (FMGs) are a prominent modern prescription Chinese patent formulation derived from the Muji decoction. Utilized in clinical practice for nearly four decades, FMGs have demonstrated efficacy in treating liver diseases. However, the precise mechanism of action remains unclear. This study investigates the hepatoprotective effects of FMGs against liver fibrosis in rats based on untargeted metabolomics and elucidates their underlying mechanisms. A comprehensive model of liver fibrosis was established with 30% CCl

Indexed as

bile metabolismFufang Muji granulesliver fibrosisManchumetabolomics

Identifiers

PMID39195542
PMCPMC11356414

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.