Evidence map›Paper›PMID 39196926›Full record

ArticleScience advances2024

Irreversibility in bacterial regulatory networks.

Yi Zhao, Thomas P Wytock, Kimberly A Reynolds, Adilson E Motter

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Generative prediction of causal gene sets responsible for complex traits.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi ZhaoDepartment of Physics and Astronomy, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-0583-8801
Thomas P WytockDepartment of Physics and Astronomy, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-5204-1064
Kimberly A ReynoldsThe Green Center for Systems Biology-Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0003-4805-0317
Adilson E MotterDepartment of Physics and Astronomy, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0003-1794-4828

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irreversibility, in which a transient perturbation leaves a system in a new state, is an emergent property in systems of interacting entities. This property has well-established implications in statistical physics but remains underexplored in biological networks, especially for bacteria and other prokaryotes whose regulation of gene expression occurs predominantly at the transcriptional level. Focusing on the reconstructed regulatory network of

Indexed as

Escherichia coliGene Expression Regulation, BacterialGene Regulatory Networks

Identifiers

PMID39196926
PMCPMC11352831

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.