Evidence map›Paper›PMID 39197941›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Neuritin Controls Axonal Branching in Serotonin Neurons: A Possible Mediator Involved in the Regulation of Depressive and Anxiety Behaviors via FGF Signaling.

Tadayuki Shimada, Kuniko Kohyama, Tomoyuki Yoshida, Kanato Yamagata

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tadayuki ShimadaChild Brain Project, Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506, Japan shimada-td@igakuken.or.jp.ORCID 0000-0001-7333-9847
Kuniko KohyamaChild Brain Project, Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506, Japan.
Tomoyuki YoshidaDepartment of Molecular Neuroscience, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Toyama 930-0194, Japan.
Kanato YamagataChild Brain Project, Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506, Japan.ORCID 0000-0001-6183-2511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal neuronal morphological features, such as dendrite branching, axonal branching, and spine density, are thought to contribute to the symptoms of depression and anxiety. However, the role and molecular mechanisms of aberrant neuronal morphology in the regulation of mood disorders remain poorly characterized. Here, we show that neuritin, an activity-dependent protein, regulates the axonal morphology of serotonin neurons. Male

Indexed as

AnxietyAxonsDepressionGPI-Linked ProteinsMice, KnockoutSerotonergic NeuronsSignal TransductionAnimalsFibroblast Growth FactorsMaleMiceMice, Inbred C57BLNerve Tissue ProteinsNeuropeptidesStress, PsychologicalFibroblast Growth FactorsGPI-Linked ProteinsNerve Tissue ProteinsNeuropeptidesNrn1 protein, mouseamygdalaanxietyaxonal morphologydepressionFGFserotonin

Identifiers

PMID39197941
PMCPMC11466069

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.