ArticleBMC public health2024
The impact of chronic diseases on the health-related quality of life of middle-aged and older adults: the role of physical activity and degree of digitization.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Implementation science in care for older adults across healthcare settings: a scoping review.Archives of public health = Archives belges de sante publique · 2026Pooled it
- Nurse-Led Interventions to Improve Health, Adherence, and Functional Outcomes in Adults and Older Adults With Multimorbidity: A Systematic Review of Randomized and Quasiexperimental Studies.Journal of nursing management · 2025Pooled it
- Association between health-related quality of life and noncommunicable diseases in South Korea: A nationwide representative study.Medicine · 2026Article
- Psychometric properties of the Arabic IMPACT Bowel Function Short Form for assessing pelvic floor dysfunctions symptoms.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026Article
- Psychosocial determinants of sexual satisfaction in older adults with multimorbidity: a cross-sectional study.BMC geriatrics · 2026Article
- Predictors of perceived quality of life in zoroastrian minority older adults with chronic diseases: a cross-sectional study in Iran.BMC geriatrics · 2026Article
- Cross-cultural adaptation and psychometric evaluation of the Chinese version of the short version of the Cognitive Reserve Index Questionnaire (s-CRIq): a cross-sectional study.BMC psychiatry · 2026Article
- Self-compassionate engagement among older adults living with chronic diseases in Kathmandu, Nepal: a qualitative descriptive study.BMC psychology · 2026Article
- A Cross-Sectional Assessment of Quality of Life Among Healthcare Professionals in North-Central Saudi Arabia: Implications for Workforce Well-Being and Policy Development.Healthcare (Basel, Switzerland) · 2026Article
- The relationship between physical activity and quality of life among community-dwelling middle-aged and older adults with type 2 diabetes: a chain mediation model of psychological resilience and exercise self-efficacy.Frontiers in endocrinology · 2026Article
- Biomimetic hydrogel micro-/nanofibers forBioactive materials · 2026Review
- Dynamic interactions between physical activity, exercise adherence, and adverse psychological states in Chinese older adults: a cross-lagged network analysis.Frontiers in public health · 2026Article
- Unveiling natural anti-inflammatory compounds for sinusitis treatments by modulating FOXP3, C5aR1, and LIF.Frontiers in immunology · 2026Review
- Seasonal, Monthly, and Holiday Patterns in Self-Monitored Step Counts Among Individuals with Prediabetes and Type 2 Diabetes: A Two-Year Analysis.International journal of environmental research and public health · 2025Observational
- Barriers to Chronic Disease Healthcare Access in Rural Eastern Cape Province, South Africa.International journal of environmental research and public health · 2025Article
- Exploring Psychological Factors and Metacognitive Beliefs in Cardiac Rehabilitation: A Single-Group Pre-Post Study.European journal of investigation in health, psychology and education · 2025Article
- Article
- Physical activity and quality of life in statin users.Family practice · 2025Article
- Prevalence, combination patterns, and quality of life factors of multimorbidity among older adults in southern China based on the health ecological model.Journal of global health · 2025Article
- Patterns of social participation among older adults and their association with self-rated health: the mediating role of activities of daily living.Aging clinical and experimental research · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of chronic diseases is on the rise worldwide, with a high mortality rate in China, posing a serious threat to the health-related quality of life (HRQoL) of middle-aged and older adults. This study explores the association between chronic diseases and the HRQoL of middle-aged and older adults, as well as the role of physical activity (PA) and degree of digitization in this relationship.
methodsThe data used in this study was obtained from the 2018 China Health and Retirement Longitudinal Study (CHARLS), which included 13,620 middle-aged and older Chinese adults (≥ 45 years). The study utilized correlation analysis, and bootstrapping to investigate the mediating role of PA and the moderating influence of the degree of digitization. Data analysis was conducted using SPSS 26.0.
resultsThe study findings indicate that the severity of chronic disease has a significant negative predictive effect on HRQoL (PCS, physical component summary; MCS, mental component summary) (PCS: β = -2.515, p < 0.01, MCS: β = -0.735, p < 0.01). Further analysis revealed that PA plays a mediating and masking role in the impact of chronic disease on PCS and MCS. Additionally, the degree of digitization moderates the relationship between chronic disease and PA, chronic disease and PCS, and PA and PCS.
conclusionFor middle-aged and older persons, chronic diseases have a detrimental effect on their HRQoL; nevertheless, PA can help. Furthermore, proper internet usage can help older individuals to some extent in mitigating the negative impact of chronic diseases. Therefore, it is encouraged to promote PA among the elderly with chronic diseases to improve their physical health, as well as to guide them in the proper use of the Internet to establish healthy behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.