Evidence map›Paper›PMID 39198821›Full record

ArticleLipids in health and disease2024

Relationship between Ikigai and longitudinal changes in serum HDL cholesterol levels: the Circulatory Risk in Communities Study (CIRCS).

Shiori Ikeda, Ai Ikeda, Kazumasa Yamagishi, Isao Muraki, Takumi Matsumura, Tomomi Kihara, Tomoko Sankai, Midori Takada, Takeo Okada, Masahiko Kiyama and 3 more

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Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shiori IkedaDepartment of Public Health, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Ai IkedaDepartment of Public Health, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Kazumasa YamagishiDepartment of Public Health, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Isao MurakiPublic Health, Department of Social Medicine, Osaka University Graduate School of Medicine, 1-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Takumi MatsumuraDepartment of Public health, Kindai University Faculty of Medicine, 377-2 Ohnohigashi, Osakasayama, Osaka, 589-8511, Japan.
Tomomi KiharaDepartment of Public Health Medicine, Insitute of Medicine, and Health Services Research and Development Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan.
Tomoko SankaiDepartment of Public Health and Nursing, Institute of Medicine, University of Tsukuba, 2 Amakubo, Tsukuba, Ibaraki, 305-0005, Japan.
Midori TakadaDepartment of Public Health and Health Systems, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, 466-8550, Japan.
Takeo OkadaOsaka Center for Cancer and Cardiovascular Disease Prevention, 1-6-107 Morinomiya, Jyoto-Ku, Osaka, Osaka, 536-8588, Japan.
Masahiko KiyamaDepartment of Public Health, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Hironori ImanoDepartment of Public health, Kindai University Faculty of Medicine, 377-2 Ohnohigashi, Osakasayama, Osaka, 589-8511, Japan.
Hiroyasu IsoInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-Ku, Tokyo, 162-8655, Japan.
Takeshi TanigawaDepartment of Public Health, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan. tataniga@juntendo.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHaving positive psychological well-being has been associated with serum high-density lipoprotein cholesterol (HDLC), but no longitudinal study to date has examined the association between Ikigai and serum HDLC. Therefore, we examined the association between Ikigai and change in serum HDLC over time using a cohort dataset spanning 2010-2018.

methodsThe study included 471 men and 776 women aged 40-74 years who underwent a cardiovascular examination in 2010 and were asked their levels of Ikigai. We combined "definitely yes" and "yes" as "with Ikigai" and recorded "a little" as "with a little Ikigai" and "no" as "without Ikigai". We measured serum HDLC using direct methods. The association between Ikigai and serum HDLC levels at baseline, and changes in this relationship during an eight-year period, were analyzed using linear mixed-effect models.

resultsAt the baseline, relative to those without Ikigai, women with Ikigai had higher serum HDLC (baseline difference in those with a little Ikigai = 7.52 mg/dl, 95% confidence interval [CI]: 1.12 to 13.9 and in those with Ikigai = 8.11 mg/dl, 95% CI: 1.54 to 14.7). The difference in serum HDLC between women with and without Ikigai remained over the eight-year follow-up period. There were no similar Ikigai-associated differences in the serum HDLC of men.

conclusionsWomen with Ikigai showed differences in serum HDLC that were observed at baseline and persisted over time.

Indexed as

Cholesterol, HDLAdultAgedCardiovascular DiseasesFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk FactorsCholesterol, HDLHDL cholesterolIkigaiLongitudinal studyPositive psychologyStress

Identifiers

PMID39198821
PMCPMC11351031

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.