Evidence map›Paper›PMID 39199359›Full record

ReviewBiomolecules2024

Biological Properties of Sandalwood Oil and Microbial Synthesis of Its Major Sesquiterpenoids.

Xiaoguang Yan, Sichone Daniel David, Guangzhao Du, Weiguo Li, Dongmei Liang, Shengxin Nie, Mingyue Ge, Chen Wang, Jianjun Qiao, Yanni Li and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaoguang YanSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.ORCID 0000-0001-9977-1849
Sichone Daniel DavidSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Guangzhao DuSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Weiguo LiSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Dongmei LiangSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Shengxin NieSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Mingyue GeSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Chen WangZhejiang Key Laboratory of Alternative Technologies for Fine Chemicals Process, Shaoxing University, Shaoxing 312000, China.
Jianjun QiaoSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Yanni LiSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Qinggele CaiyinSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.

Funding

China Postdoctoral Science Foundation 2023M742602National Key R&D Program of China 2020YFA0906800National Natural Science Foundation of China 32300055
6 · The paper itself

Abstract

Sandalwood essential oil is extracted from the heartwood part of mature sandalwood and is known for its pleasant fragrance and exceptional medicinal activities, including antimicrobial, antitumor, and anti-inflammatory properties. The (Z)-α-santalol and (Z)-β-santalol are the most vital ingredients contributing to sandalwood oil's bioactivities and unique woody odor characteristics. Metabolic engineering strategies have shown promise in transforming microorganisms such as yeast and bacteria into effective cell factories for enhancing the production of vital sesquiterpenes (santalene and santalol) found in sandalwood oil. This review aims to summarize sources of sandalwood oil, its components/ingredients, and its applications. It also highlights the biosynthesis of santalene and santalol and the various metabolic engineering strategies employed to reconstruct and enhance santalene and santalol biosynthesis pathways in heterologous hosts.

Indexed as

Metabolic EngineeringPlant OilsSantalumSesquiterpenesBacteriaHumansPolycyclic SesquiterpenesPlant OilsPolycyclic Sesquiterpenessandalwood oilSesquiterpenesbiosynthesismetabolic engineeringsandalwood oilsantalenesantalolsesquiterpenes

Identifiers

PMID39199359
PMCPMC11352278

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.