Evidence map›Paper›PMID 39199994›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Randomized, Double-Blind, Placebo-Controlled Study of Anti-Mycobacterial Therapy (RHB-104) in Active Crohn's Disease.

David Y Graham, Saleh A Naser, Thomas Borody, Zbigniew Hebzda, Harry Sarles, Scott Levenson, Robert Hardi, Tomasz Arłukowicz, Petar Svorcan, Reza Fathi and 7 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Pathogens (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Viewpoint: The Use of Antimycobacterial (Anti-MAP) Therapies in the Treatment of Active Luminal Crohn's Disease.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

David Y GrahamDepartments of Medicine, Molecular Virology, and Microbiology, Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-6908-8317
Saleh A NaserBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0001-9222-4527
Thomas BorodyCenter for Digestive Diseases, Sydney 2046, Australia.ORCID 0000-0002-0519-4698
Zbigniew HebzdaSpecjalistyczne Centrum Medyczne Unimedica, 31-271 Krakow, Poland.
Harry SarlesDigestive Health Associates of Texas (DHAT) Research Institute, Garland, TX 75044, USA.
Scott LevensonDigestive Care Associates, Inc., San Carlos, CA 94070, USA.
Robert HardiDepartment of Gastroenterology, George Washington University Medical School, Washington, DC 20052, USA.
Tomasz ArłukowiczCollegium Medicum, University of Warmia and Mazury, 10-082 Olsztyn, Poland.ORCID 0000-0002-7066-4211
Petar SvorcanSchool of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Reza FathiRedHill Biopharma, Ltd., Tel Aviv 6473921, Israel.
Aida BibliowiczRedHill Biopharma, Ltd., Tel Aviv 6473921, Israel.
Patricia AndersonRedHill Biopharma, Ltd., Tel Aviv 6473921, Israel.
Patrick McLeanRedHill Biopharma, Ltd., Tel Aviv 6473921, Israel.
Clara FehrmannCEEF Solutions, Pointe-Claire, QC H9S 4L7, Canada.
M Scott HarrisMiddleburg Consultants, Takoma Park, MD 20912, USA.
Shuhong ZhaoSyneos Health, Morrisville, NC 27560, USA.
Ira N KalfusM2g Consulting, Inc., New York, NY 10024, USA.

Funding

RedHill Biopharma, Ltd., Tel Aviv, Israel N/A
6 · The paper itself

Abstract

This study, conducted between 4 October 2013, and 30 November 2018, tested the hypothesis that triple antimicrobial therapy, targeting

Indexed as

clarithromycinclinical trialclofazimineCrohn’s diseaseMycobacterium avium subspecies paratuberculosisRHB-104rifabutin

Identifiers

PMID39199994
PMCPMC11350828

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.