Evidence mapPaperPMID 39200296Full record

ReviewBiomedicines2024

Cholesterol Metabolism and Urinary System Tumors.

Songyuan Yang, Zehua Ye, Jinzhuo Ning, Peihan Wang, Xiangjun Zhou, Wei Li, Fan Cheng

Abstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Songyuan YangDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Zehua YeDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Jinzhuo NingDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID 0000-0002-2955-1629
Peihan WangDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Xiangjun ZhouDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Wei LiDepartment of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Fan ChengDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID 0000-0002-3471-6221

Funding

National Natural Science Foundation of China 82272232
6 · The paper itself

Abstract

Cancers of the urinary system account for 13.1% of new cancer cases and 7.9% of cancer-related deaths. Of them, renal cancer, bladder cancer, and prostate cancer are most prevalent and pose a substantial threat to human health and the quality of life. Prostate cancer is the most common malignant tumor in the male urinary system. It is the second most common type of malignant tumor in men, with lung cancer surpassing its incidence and mortality. Bladder cancer has one of the highest incidences and is sex-related, with men reporting a significantly higher incidence than women. Tumor development in the urinary system is associated with factors, such as smoking, obesity, high blood pressure, diet, occupational exposure, and genetics. The treatment strategies primarily involve surgery, radiation therapy, and chemotherapy. Cholesterol metabolism is a crucial physiological process associated with developing and progressing urinary system tumors. High cholesterol levels are closely associated with tumor occurrence, invasion, and metastasis. This warrants thoroughly investigating the role of cholesterol metabolism in urinary system tumors and identifying novel treatment methods for the prevention, early diagnosis, targeted treatment, and drug resistance of urinary system tumors.

Indexed as

bladder cancercholesterol metabolismprostate cancerrenal cancerurinary system tumors

Identifiers

PMID39200296
PMCPMC11351655

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.