Evidence mapPaperPMID 39200424Full record

ArticleFoods (Basel, Switzerland)2024

Integrated Analysis of Ginsenoside Content and Biomarker Changes in Processed Ginseng: Implications for Anti-Cancer Mechanisms.

Biyu Guo, Yingli Liang, Biru Fu, Jiayi Luo, Xingchen Zhou, Ruifeng Ji, Xin He

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Biyu GuoSchool of Traditional Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou 510006, China.ORCID 0009-0002-8726-1301
Yingli LiangSchool of Traditional Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Biru FuSchool of Traditional Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Jiayi LuoSchool of Traditional Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Xingchen ZhouJingji (Guangzhou) Biotechnology Co., Ltd., Guangzhou 510006, China.
Ruifeng JiSchool of Traditional Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Xin HeSchool of Traditional Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou 510006, China.

Funding

National Natural Science Foundation of China 48-44148079
6 · The paper itself

Abstract

Black ginseng is the processed product of ginseng, and it has been found that the content and types of rare ginsenosides increased after processing. However, there is limited research on the ginsenoside differences between cultivated and forest ginseng before and after processing and among various plant parts. This study investigated the effects of processing on ginsenosides in different parts of cultivated and forest ginseng. After processing, the contents of Re, Rg1, S-Rg3, Rg5, R-Rh1, Rk1, Rk3, and F4 were significantly increased or decreased, the growth age of forest ginseng was not proportional to the content of ginsenosides, and the differences in ginsenoside content in ginseng from different cultivation methods were relatively small. Chemometric analysis identified processing biomarkers showing varying percentage changes in different parts. Network pharmacology predicted the EGFR/PI3K/Akt/mTOR pathway as a potential key pathway for the anti-cancer effect of black ginseng.

Indexed as

chemometriccultivated ginsengforest ginsengprocessingrare ginsenosidesUPLC-MS

Identifiers

PMID39200424
PMCPMC11353654

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.