Evidence map›Paper›PMID 39201266›Full record

ArticleInternational journal of molecular sciences2024

The Inhibitory Effects of Maclurin on Fatty Acid Synthase and Adipocyte Differentiation.

Ji Young Hwang, Hyeon Hak Jeong, Jiwon Baek, Jiyun Lee, Heeyeon Ryu, Jae-Il Kim, Bonggi Lee

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ji Young HwangDepartment of Smart Green Technology Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Hyeon Hak JeongDepartment of Smart Green Technology Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Jiwon BaekDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of Korea.
Jiyun LeeDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of Korea.
Heeyeon RyuDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of Korea.
Jae-Il KimDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0002-6186-5492
Bonggi LeeDepartment of Smart Green Technology Engineering, Pukyong National University, Busan 48513, Republic of Korea.

Funding

National Research Foundation of Korea RS-2023-00274576National Research Foundation of Korea (NRF) grant funded by the Ministry of Education 2021R1A6A1A03039211
6 · The paper itself

Abstract

Obesity is a complex health condition characterized by excessive adipose tissue accumulation, leading to significant metabolic disturbances such as insulin resistance and cardiovascular diseases. Fatty acid synthase (FAS), a key enzyme in lipogenesis, has been identified as a potential therapeutic target for obesity due to its role in adipocyte differentiation and lipid accumulation. This study employed a multidisciplinary approach involving in silico and in vitro analyses to investigate the anti-adipogenic properties of maclurin, a natural phenolic compound derived from

Indexed as

3T3-L1 CellsAdipocytesAdipogenesisCell DifferentiationMolecular Docking Simulation4-ButyrolactoneAnimalsCell SurvivalFatty Acid SynthasesLipid MetabolismMicePlant LectinsPPAR gamma4-Butyrolactone4-methylene-2-octyl-5-oxofuran-3-carboxylic acidFatty Acid SynthasesmaclurinPlant LectinsPPAR gamma3T3-L1 adipocytesadipogenesisfatty acid synthasemaclurinobesity

Identifiers

PMID39201266
PMCPMC11354920

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.