Evidence map›Paper›PMID 39201268›Full record

ArticleInternational journal of molecular sciences2024

Modulation of Ceramide-Induced Apoptosis in Enteric Neurons by Aryl Hydrocarbon Receptor Signaling: Unveiling a New Pathway beyond ER Stress.

Mallappa Anitha, Supriya M Kumar, Imhoi Koo, Gary H Perdew, Shanthi Srinivasan, Andrew D Patterson

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Enteric nervous system as a therapeutic target in gastrointestinal disorders.World journal of gastrointestinal pharmacology and therapeutics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mallappa AnithaDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0009-0007-6313-0063
Supriya M KumarDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Imhoi KooDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-5816-0627
Gary H PerdewDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Shanthi SrinivasanDepartment of Digestive Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA.
Andrew D PattersonDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-2073-0070

Funding

Activation of the Ah receptor and epithelial integrityR35ES028244 · NIEHS · PENNSYLVANIA STATE UNIVERSITY, THE · PI PERDEW, GARY H. · 2017 to 2024
$6.2M
Environmental Chemical Impact on the Host-Microbiome InteractionR35ES035027 · NIEHS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Andrew Patterson · 2023 to 2026
$3.6M
Acquisition of an Orbitrap Fusion Lumos Tribid Mass Spectrometer to Accelerate Metabolite Identification and Pathway AnalysisS10OD021750 · OD · PENNSYLVANIA STATE UNIVERSITY, THE · PI PATTERSON, ANDREW · 2017 to 2017
$966k
NIEHS NIH HHS 028244NIEHS NIH HHS 035027NIEHS NIH HHS R35 ES028244NIEHS NIH HHS R35 ES035027NIH HHS S10 OD021750USDA This work is/was supported by the USDA National Institute of Food and Agriculture and Hatch Appropriations under Project #PEN04917 and Accession #7006412.
6 · The paper itself

Abstract

2,3,7,8-tetrachlorodibenzo-

Indexed as

ApoptosisCeramidesEndoplasmic Reticulum StressEnteric Nervous SystemNeuronsReceptors, Aryl HydrocarbonAnimalsCells, CulturedGlycogen Synthase Kinase 3 betaMaleMiceMice, Inbred C57BLMice, TransgenicPolychlorinated DibenzodioxinsProto-Oncogene Proteins c-aktSphingolipidsCeramidesGlycogen Synthase Kinase 3 betaPolychlorinated DibenzodioxinsProto-Oncogene Proteins c-aktReceptors, Aryl HydrocarbonSphingolipidsAHRapoptosisceramidescytotoxicityENSTCDD

Identifiers

PMID39201268
PMCPMC11354200

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.