Evidence map›Paper›PMID 39201410›Full record

ArticleInternational journal of molecular sciences2024

Humanized L184Q Mutated Surfactant Protein C Gene Alters Alveolar Type 2 Epithelial Cell Fate.

Krishan G Jain, Yang Liu, Runzhen Zhao, Preeti J Muire, Jiwang Zhang, Qun Sophia Zang, Hong-Long Ji

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Surfactant Protein-C Regulates Alveolar Type 2 Epithelial Cell Lineages via the CD74 Receptor.Journal of respiratory biology and translational medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Krishan G JainDepartment of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.ORCID 0000-0002-1392-7038
Yang LiuDepartment of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Runzhen ZhaoDepartment of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Preeti J MuireBurn and Shock Trauma Research Institute, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Jiwang ZhangDepartment of Cancer Biology, Oncology Institute, Cardinal Bernardin Cancer Center, Loyola University Medical Center, Maywood, IL 60153, USA.
Qun Sophia ZangDepartment of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Hong-Long JiDepartment of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.

Funding

NOVEL PARACRINE MECHANISMS FOR CELL-BASED THERAPY OF INJURED LUNGSR01HL134828 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI JI, HONG-LONG · 2017 to 2025
$3.4M
NHLBI NIH HHS R01 HL134828NIH HHS HL134828
6 · The paper itself

Abstract

Alveolar type 2 epithelial (AT2) cells synthesize surfactant protein C (SPC) and repair an injured alveolar epithelium. A mutated surfactant protein C gene (

Indexed as

Alveolar Epithelial CellsPulmonary Surfactant-Associated Protein CAnimalsCell DifferentiationCell LineageFemaleHumansMaleMembrane GlycoproteinsMiceMice, Inbred C57BLMutationOrganoidsMembrane GlycoproteinsPulmonary Surfactant-Associated Protein CSFTPC protein, humanSftpc protein, mousealveolar type 2 epithelial celldifferentiationL184Q mutationproliferationre-alveolarizationsurfactant protein C

Identifiers

PMID39201410
PMCPMC11354303

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.