Evidence map›Paper›PMID 39201504›Full record

ArticleInternational journal of molecular sciences2024

Is Exon Skipping a Viable Therapeutic Approach for Vascular Ehlers-Danlos Syndrome with Mutations in

Sasiwimon Utama, Jessica M Cale, Chalermchai Mitrpant, Sue Fletcher, Steve D Wilton, May T Aung-Htut

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sasiwimon UtamaDepartment of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Jessica M CaleCentre of Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia.ORCID 0000-0001-7218-3027
Chalermchai MitrpantDepartment of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.ORCID 0000-0001-9311-7977
Sue FletcherCentre of Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia.ORCID 0000-0002-8632-641X
Steve D WiltonCentre of Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia.
May T Aung-HtutCentre of Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia.ORCID 0000-0002-6379-2303

Funding

NHMRC APP1144791
6 · The paper itself

Abstract

Vascular Ehlers-Danlos syndrome or Ehlers-Danlos syndrome type IV (vEDS) is a connective tissue disorder characterised by skin hyperextensibility, joint hypermobility and fatal vascular rupture caused by

Indexed as

Collagen Type IIIEhlers-Danlos SyndromeExonsFibroblastsMutationOligonucleotides, AntisenseCells, CulturedEhlers-Danlos Syndrome, Type IVExtracellular MatrixHumansMaleRNA SplicingCOL3A1 protein, humanCollagen Type IIIOligonucleotides, Antisenseantisense oligonucleotidesCOL3A1collagen IIIVascular Ehler-Danlos Syndrome

Identifiers

PMID39201504
PMCPMC11354334

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.