Evidence map›Paper›PMID 39201665›Full record

ArticleInternational journal of molecular sciences2024

Capsaicin Reduces Obesity by Reducing Chronic Low-Grade Inflammation.

Jiaxin Yang, Wanyi Li, Yuanwei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiaxin YangCollege of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Wanyi LiCollege of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Yuanwei WangCollege of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.ORCID 0000-0002-5588-8356

Funding

The Fundamental Research Funds for the Central Universities，Southwest Minzu University ZYN2024085The National Natural Science Foundation of Sichuan Province 2022NSFSC0584
6 · The paper itself

Abstract

Chronic low-grade inflammation (CLGI) is associated with obesity and is one of its pathogenetic mechanisms. Lipopolysaccharide (LPS), a component of Gram-negative bacterial cell walls, is the principal cause of CLGI. Studies have found that capsaicin significantly reduces the relative abundance of LPS-producing bacteria. In the present study,

Indexed as

CapsaicinInflammationLipopolysaccharidesMice, Inbred C57BLObesityToll-Like Receptor 4TRPV Cation ChannelsAnimalsCaco-2 CellsDiet, High-FatHumansIntestinal MucosaMaleMiceMice, KnockoutOccludinCapsaicinLipopolysaccharidesOccludinToll-Like Receptor 4TRPV1 protein, mouseTRPV Cation ChannelsZonula Occludens-1 Proteinanti-obesitycapsaicinchronic low-grade inflammationgut barriergut microbiota

Identifiers

PMID39201665
PMCPMC11354495

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.