Evidence map›Paper›PMID 39201749›Full record

ArticleInternational journal of molecular sciences2024

Characterization and Functional Analysis of the 17-Beta Hydroxysteroid Dehydrogenase 2 (

Ruyi Chen, Haoyu Zhu, Xiaoling Zhang, Lingli Li, Jinglin Xu, Zhimin Tan, Jialin Su, Ke Feng, Kaili Chen, Hongyan Xu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Identification of IPF specific genes expressed by lung tissue-derived fibroblasts using next generation sequencing.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruyi ChenIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.ORCID 0009-0004-9185-7444
Haoyu ZhuIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.
Xiaoling ZhangIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.
Lingli LiIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.
Jinglin XuIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.
Zhimin TanIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.
Jialin SuIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.
Ke FengIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.
Kaili ChenIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.
Hongyan XuIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City & College of Fisheries, Key Laboratory of Freshwater Fish Reproduction and Development Ministry of Education, Key Laboratory of Aquatic Sciences of Chongqing, Southwest University, Chongqing 402460, China.ORCID 0000-0002-4916-2567

Funding

Fundamental Research Funds for the Central Universities SWU020014Natural Science Foundation of Chongqing City CSTB2023NSCQ MSX0325the National Key Research and Development Program of China 2022YFD2400902The National Key Research and Development Program of Tibet Autonomous Region XZ202202ZY002N
6 · The paper itself

Abstract

In mammals, 17-beta hydroxysteroid dehydrogenase 2 (Hsd17b2) enzyme specifically catalyzes the oxidation of the C17 hydroxyl group and efficiently regulates the activities of estrogens and androgens to prevent diseases induced by hormone disorders. However, the functions of the

Indexed as

Cloning, MolecularEels17-Hydroxysteroid DehydrogenasesAmino Acid SequenceAnimalsFemaleFish ProteinsGene Expression Regulation, DevelopmentalMaleOvaryPhylogenySex Determination ProcessesSex DifferentiationSmegmamorphaTestis17-Hydroxysteroid DehydrogenasesFish Proteinschemical in situ hybridizationhormone inductionhsd17b2ricefield eelsex reversal

Identifiers

PMID39201749
PMCPMC11354438

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.