Evidence map›Paper›PMID 39202788›Full record

ArticleLife (Basel, Switzerland)2024

Barium Chloride-Induced Cardiac Arrhythmia Mouse Model Exerts an Experimental Arrhythmia for Pharmacological Investigations.

Mengting Zeng, Liyue Huang, Xiaohui Zheng, Lebin Weng, Ching-Feng Weng

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mengting ZengFunctional Physiology Section, Department of Basic Medical Science, Xiamen Medical College, Xiamen 361023, China.
Liyue HuangFunctional Physiology Section, Department of Basic Medical Science, Xiamen Medical College, Xiamen 361023, China.
Xiaohui ZhengFunctional Physiology Section, Department of Basic Medical Science, Xiamen Medical College, Xiamen 361023, China.ORCID 0000-0002-7094-1602
Lebin WengFunctional Physiology Section, Department of Basic Medical Science, Xiamen Medical College, Xiamen 361023, China.
Ching-Feng WengFunctional Physiology Section, Department of Basic Medical Science, Xiamen Medical College, Xiamen 361023, China.ORCID 0000-0002-9747-8697

Funding

Xiamen Medical College K2019-01Xiamen Medical College K2020-07
6 · The paper itself

Abstract

aimCardiac arrhythmias are among the most important pathologies that cause sudden death. The exploration of new therapeutic options against arrhythmias with low undesirable effects is of paramount importance.

methodsHowever, the convenient and typical animal model for screening the potential lead compound becomes a very critical modality, particularly in anti-arrhythmia. In this study, mice were intraperitoneally (i.p.) injected with BaCl

resultsElectrocardiogram (ECG) showed that the majority of mice repeatedly developed ventricular bigeminy, ventricular tachycardia (VT), and ventricular fibrillation (VF) after BaCl

conclusionsThis study brings an alternative experimental model to investigate antiarrhythmic theories and provides a promising approach to discovering new interventions for acute arrhythmias.

Indexed as

BaCl2-inducedcardiac arrhythmiaelectrocardiogramintraperitonealsudden cardiac death

Identifiers

PMID39202788
PMCPMC11355614

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.