Evidence map›Paper›PMID 39202940›Full record

ReviewMolecules (Basel, Switzerland)2024

Plant-Derived Terpenoids: A Plethora of Bioactive Compounds with Several Health Functions and Industrial Applications-A Comprehensive Overview.

José S Câmara, Rosa Perestrelo, Rui Ferreira, Cristina V Berenguer, Jorge A M Pereira, Paula C Castilho

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Molecules (Basel, Switzerland) · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Phytochemistry and Pharmacological Potential of the GenusPharmaceuticals (Basel, Switzerland) · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Analysis of the Chemical Composition ofMolecules (Basel, Switzerland) · 2026
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

José S CâmaraCQM-Centro de Química da Madeira, NPRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal.ORCID 0000-0003-1965-3151
Rosa PerestreloCQM-Centro de Química da Madeira, NPRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal.ORCID 0000-0002-7223-1022
Rui FerreiraCQM-Centro de Química da Madeira, NPRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal.ORCID 0000-0003-1467-4332
Cristina V BerenguerCQM-Centro de Química da Madeira, NPRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal.ORCID 0000-0002-1762-1175
Jorge A M PereiraCQM-Centro de Química da Madeira, NPRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal.ORCID 0000-0003-0316-5348
Paula C CastilhoCQM-Centro de Química da Madeira, NPRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal.ORCID 0000-0002-8303-4286

Funding

Agencia Regional para o Desenvolvimento da Investigacao Tecnologia e Inovacao M1420-01-0145-FEDER-000005Fundação para a Ciência e Tecnologia UIDB/00674/2020Fundação para a Ciência e Tecnologia UIDP/00674/2020Madeira 14-20 PROEQUIPRAM program, M14-20 M1420-01-0145-FEDER-000008
6 · The paper itself

Abstract

Terpenoids are a large class of natural secondary plant metabolites which are highly diverse in structure, formed from isoprene units (C-5), associated with a wide range of biological properties, including antioxidant, antimicrobial, anti-inflammatory, antiallergic, anticancer, antimetastatic, antiangiogenesis, and apoptosis induction, and are considered for potential application in the food, cosmetics, pharmaceutical, and medical industries. In plants, terpenoids exert a variety of basic functions in growth and development. This review gives an overview, highlighting the current knowledge of terpenoids and recent advances in our understanding of the organization, regulation, and diversification of core and specialized terpenoid metabolic pathways and addressing the most important functions of volatile and non-volatile specialized terpenoid metabolites in plants. A comprehensive description of different aspects of plant-derived terpenoids as a sustainable source of bioactive compounds, their biosynthetic pathway, the several biological properties attributed to these secondary metabolites associated with health-promoting effects, and their potential industrial applications in several fields will be provided, and emerging and green extraction methods will also be discussed. In addition, future research perspectives within this framework will be highlighted. Literature selection was carried out using the National Library of Medicine, PubMed, and international reference data for the period from 2010 to 2024 using the keyword "terpenoids". A total of 177,633 published papers were found, of which 196 original and review papers were included in this review according to the criteria of their scientific reliability, their completeness, and their relevance to the theme considered.

Indexed as

TerpenesAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsHumansPlant ExtractsPlantsAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsPlant ExtractsTerpenesbioactive compoundsbiosourcesbiosynthesishealth benefitsindustrial applicationsterpenoids

Identifiers

PMID39202940
PMCPMC11357518

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.