Evidence map›Paper›PMID 39203467›Full record

ArticleMicroorganisms2024

Impact of Human Milk Oligosaccharides and Probiotics on Gut Microbiome and Mood in Autism: A Case Report.

Luana Aldegheri, Feras Kharrat, Andrea Conti, Fabio Monica, Francesca Busa, Giuseppina Campisciano, Nunzia Zanotta, Carolina Cason, Manola Comar

Abstract readCase Reports
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luana AldegheriInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0009-0004-9116-2685
Feras KharratInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0009-0004-9853-0161
Andrea ContiInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0009-0001-2127-4022
Fabio MonicaDepartment of Gastroenterology and Endoscopy, Trieste University Hospital, Strada di Fiume 447, 34149 Trieste, Italy.
Francesca BusaScuola Microbioma Torino, 10100 Torino, Italy.
Giuseppina CampiscianoInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0000-0002-2307-5537
Nunzia ZanottaInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.
Carolina CasonInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0000-0002-3456-4395
Manola ComarInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.

Funding

Ministero della Salute RC 20/21
6 · The paper itself

Abstract

Recent evidence has highlighted the role of the gut-brain axis in the progression of autism spectrum disorder (ASD), with significant changes in the gut microbiome of individuals with this condition. This report investigates the effects of probiotics and human milk oligosaccharide (HMO) supplements on the gut microbiome, inflammatory cytokine profile, and clinical outcomes in an ASD adolescent with chronic gastrointestinal dysfunction and cognitive impairment. Following treatment, we observed a decrease in proinflammatory cytokines' concentration alongside

Indexed as

autism spectrum disordercytokinesHMOsmicrobiomenext-generation sequencing

Identifiers

PMID39203467
PMCPMC11356532

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.