Evidence mapPaperPMID 39203539Full record

ArticleMicroorganisms2024

A Situation Analysis of the Capacity of Laboratories in Faith-Based Hospitals in Zambia to Conduct Surveillance of Antimicrobial Resistance: Opportunities to Improve Diagnostic Stewardship.

Doreen Mainza Shempela, Steward Mudenda, Maisa Kasanga, Victor Daka, Mundia Hendrix Kangongwe, Mapeesho Kamayani, Jay Sikalima, Baron Yankonde, Cynthia Banda Kasonde, Ruth Nakazwe and 9 more

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Doreen Mainza ShempelaChurches Health Association of Zambia, Lusaka 10101, Zambia.ORCID 0009-0003-4945-6746
Steward MudendaDepartment of Pharmacy, School of Health Sciences, University of Zambia, Lusaka 10101, Zambia.ORCID 0000-0003-1692-8981
Maisa KasangaDepartment of Pathology and Microbiology, University Teaching Hospitals, Lusaka 10101, Zambia.ORCID 0000-0003-1724-7934
Victor DakaDepartment of Public Health, School of Medicine, Copperbelt University, Ndola 10101, Zambia.ORCID 0000-0001-9490-5609
Mundia Hendrix KangongweChest Diseases Laboratory, Ministry of Health, Lusaka 10101, Zambia.
Mapeesho KamayaniChurches Health Association of Zambia, Lusaka 10101, Zambia.
Jay SikalimaChurches Health Association of Zambia, Lusaka 10101, Zambia.ORCID 0009-0001-8589-0676
Baron YankondeChurches Health Association of Zambia, Lusaka 10101, Zambia.ORCID 0009-0001-4052-5288
Cynthia Banda KasondeChurches Health Association of Zambia, Lusaka 10101, Zambia.
Ruth NakazweDepartment of Pathology and Microbiology, University Teaching Hospitals, Lusaka 10101, Zambia.
Andrew MwandilaChurches Health Association of Zambia, Lusaka 10101, Zambia.
Fatim ChamGlobal Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), 1201 Geneva, Switzerland.
Michael NjugunaGlobal Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), 1201 Geneva, Switzerland.
Bertha SimwakaGlobal Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), 1201 Geneva, Switzerland.
Linden MorrisonGlobal Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), 1201 Geneva, Switzerland.
Joseph Yamweka ChizimuAntimicrobial Resistance Coordinating Committee, Zambia National Public Health Institute, Lusaka 10101, Zambia.
John Bwalya MumaDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.ORCID 0000-0001-6180-4051
Roma ChilengiAntimicrobial Resistance Coordinating Committee, Zambia National Public Health Institute, Lusaka 10101, Zambia.
Karen SichingaChurches Health Association of Zambia, Lusaka 10101, Zambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a public health problem exacerbated by the overuse and misuse of antibiotics and the inadequate capacity of laboratories to conduct AMR surveillance. This study assessed the capacity of laboratories in seven faith-based hospitals to conduct AMR testing and surveillance in Zambia. This multi-facility, cross-sectional exploratory study was conducted from February 2024 to April 2024. We collected and analysed data using the self-scoring Laboratory Assessment of Antibiotic Resistance Testing Capacity (LAARC) tool. This study found an average score of 39%, indicating a low capacity of laboratories to conduct AMR surveillance. The highest capacity score was 47%, while the lowest was 25%. Only one hospital had a full capacity (100%) to utilise a laboratory information system (LIS). Three hospitals had a satisfactory capacity to perform data management with scores of 83%, 85%, and 95%. Only one hospital had a full capacity (100%) to process specimens, and only one hospital had good safety requirements for a microbiology laboratory, with a score of 89%. This study demonstrates that all the assessed hospitals had a low capacity to conduct AMR surveillance, which could affect diagnostic stewardship. Therefore, there is an urgent need to strengthen the microbiology capacity of laboratories to enhance AMR surveillance in Zambia.

Indexed as

antimicrobial resistancebacteriologylaboratory capacitysurveillanceZambia

Identifiers

PMID39203539
PMCPMC11357258

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.