Evidence map›Paper›PMID 39203773›Full record

ArticleNutrients2024

The Effects of Acute Beetroot Juice Intake on Glycemic and Blood Pressure Responses When Controlling for Medication in Individuals with Type 2 Diabetes: A Pilot Study.

Andrew P Tyler, Braxton A Linder, Karina Ricart, Christian E Behrens, Fernando Ovalle, Rakesh P Patel, Gordon Fisher

Registry-linked trialAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07560800 (Effect of Beetroot Juice on Cardiovascular and Autonomic Responses During and After Exercise in Adults With Type 2 Diabetes), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07560800 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Beetroot Juice on Cardiovascular and Autonomic Responses During and After Exercise in Adults With Type 2 Diabetes

TypeinterventionalSponsorOxford Brookes UniversityRan2026 to 2026Enrolled20ConditionsType 2 Diabetes Mellitus, Hypertension, Autonomic Nervous System DiseasesArmsBeetroot juice, Nitrate-depleted Beetroot Juice Placebo
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew P TylerDepartment of Human Studies, School of Education and Human Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Braxton A LinderDepartment of Kinesiology, School of Public Health, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0001-6825-5622
Karina RicartCenter for Free Radical Biology, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-5737-8248
Christian E BehrensBayer Consumer Health Care, Whippany, NJ 07981, USA.
Fernando OvalleDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-6711-071X
Rakesh P PatelCenter for Free Radical Biology, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-1526-4303
Gordon FisherDepartment of Human Studies, School of Education and Human Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-9191-3774

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI James O Hill · 2000 to 2026
$31.9M
NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

Physical inactivity and poor dietary choices contribute to the rise in cardiometabolic diseases in the United States. It remains critical to identify strategies that may mitigate the negative impact of these behaviors. Several studies have shown that the consumption of dietary inorganic nitrate may improve vascular health and glucose regulation in animal models and some human studies. However, the improvements in glucose regulation have yet to be corroborated in humans with type 2 diabetes (T2D). Therefore, the purpose of this study was to assess the acute effects of beetroot juice (BRJ) on glycemic and hemodynamic responses in individuals with T2D while controlling for medication. Seven participants with a clinical diagnosis of T2D were recruited into this study and were temporarily removed from blood pressure- and glucose-lowering medications. Hemodynamic measurements (pulsewave velocity) and an oral glucose tolerance test (glycemic response) were measured following consumption of either BRJ or a denitrolized placebo. Saliva and blood samples were collected at baseline and two and four hours post supplementation to measure changes in nitrate and nitrite concentrations. We detected significant improvements in total plasma glucose exposure (

Indexed as

Beta vulgarisBlood GlucoseBlood PressureDiabetes Mellitus, Type 2Fruit and Vegetable JuicesNitratesAdultAgedDouble-Blind MethodFemaleGlucose Tolerance TestHumansMaleMiddle AgedNitritesPilot ProjectsBlood GlucoseNitratesNitritesbeetroot juicecardiometabolic healthdietary nitrateglucose uptakeinsulin resistancetype 2 diabetesvascular health

Identifiers

PMID39203773
PMCPMC11357045

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.