Evidence map›Paper›PMID 39205185›Full record

ArticleViruses2024

Comparative Transcriptomic Analyses of Peripheral Blood Mononuclear Cells of COVID-19 Patients without Pneumonia and with Severe Pneumonia in the First Year of Follow-Up.

Ozgecan Kayalar, Pelin Duru Cetinkaya, Vahap Eldem, Serap Argun Baris, Nurdan Kokturk, Selim Can Kuralay, Hadi Rajabi, Nur Konyalilar, Deniz Mortazavi, Seval Kubra Korkunc and 29 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors.

Ozgecan KayalarKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.ORCID 0000-0001-9107-2381
Pelin Duru CetinkayaDepartment of Pulmonary Medicine, Faculty of Medicine, Cukurova University, Adana 01790, Türkiye.
Vahap EldemDepartment of Biology, Science Faculty, Istanbul University, Istanbul 34134, Türkiye.ORCID 0000-0003-3767-5661
Serap Argun BarisDepartment of Pulmonary Medicine, Faculty of Medicine, Kocaeli University, Kocaeli 41380, Türkiye.ORCID 0000-0002-4429-9441
Nurdan KokturkDepartment of Pulmonary Medicine, Faculty of Medicine, Gazi University, Ankara 06500, Türkiye.ORCID 0000-0002-2889-7265
Selim Can KuralayDepartment of Biology, Science Faculty, Istanbul University, Istanbul 34134, Türkiye.
Hadi RajabiKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.ORCID 0000-0001-6086-591X
Nur KonyalilarKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.ORCID 0000-0003-3693-6508
Deniz MortazaviKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.
Seval Kubra KorkuncKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.
Sinem ErkanKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.
Gizem Tuşe AksoyKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.
Gul EyikudamaciKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.
Pelin Pinar DenizDepartment of Pulmonary Medicine, Faculty of Medicine, Cukurova University, Adana 01790, Türkiye.
Oya Baydar ToprakDepartment of Pulmonary Medicine, Faculty of Medicine, Cukurova University, Adana 01790, Türkiye.ORCID 0000-0001-7320-976X
Pinar Yildiz GulhanDepartment of Pulmonary Medicine, Faculty of Medicine, Duzce University, Duzce 81620, Türkiye.
Gulseren SagcanDepartment of Pulmonary Medicine, Altunizade Acibadem Hospital, Istanbul 34662, Türkiye.
Neslihan KoseDepartment of Pulmonary Medicine, Bilecik Training and Research Hospital, Bilecik 11230, Türkiye.
Aysegul Tomruk ErdemDepartment of Pulmonary Medicine, Faculty of Medicine, Zonguldak Bulent Ecevit University, Zonguldak 67100, Türkiye.ORCID 0000-0002-5346-9107
Fusun FakiliDepartment of Pulmonary Medicine, Faculty of Medicine, Gaziantep University, Gaziantep 27310, Türkiye.
Onder OzturkDepartment of Pulmonary Medicine, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Türkiye.ORCID 0000-0001-8570-2172
Ilknur BasyigitDepartment of Pulmonary Medicine, Faculty of Medicine, Kocaeli University, Kocaeli 41380, Türkiye.
Hasim BoyaciDepartment of Pulmonary Medicine, Faculty of Medicine, Kocaeli University, Kocaeli 41380, Türkiye.
Emel AzakDepartment of Infectious Disease and Clinical Microbiology, Faculty of Medicine, Kocaeli University, Kocaeli 41380, Türkiye.
Tansu Ulukavak CiftciDepartment of Pulmonary Medicine, Faculty of Medicine, Gazi University, Ankara 06500, Türkiye.
Ipek Kivilcim OguzulgenDepartment of Pulmonary Medicine, Faculty of Medicine, Gazi University, Ankara 06500, Türkiye.
Hasan Selcuk OzgerDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Gazi University, Ankara 06500, Türkiye.
Pinar Aysert YildizDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Gazi University, Ankara 06500, Türkiye.
Ismail HantaDepartment of Pulmonary Medicine, Faculty of Medicine, Cukurova University, Adana 01790, Türkiye.ORCID 0000-0001-8610-2937
Ozlem AtaogluDepartment of Pulmonary Medicine, Faculty of Medicine, Duzce University, Duzce 81620, Türkiye.
Merve ErcelikDepartment of Pulmonary Medicine, Faculty of Medicine, Duzce University, Duzce 81620, Türkiye.
Caglar CuhadarogluDepartment of Pulmonary Medicine, Altunizade Acibadem Hospital, Istanbul 34662, Türkiye.
Hacer Kuzu OkurDepartment of Pulmonary Medicine, Altunizade Acibadem Hospital, Istanbul 34662, Türkiye.
Muge Meltem TorDepartment of Pulmonary Medicine, Faculty of Medicine, Zonguldak Bulent Ecevit University, Zonguldak 67100, Türkiye.
Esra Nurlu TemelDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Türkiye.ORCID 0000-0003-4618-168X
Seval KulDepartment of Biostatistics, Faculty of Medicine, Gaziantep University, Gaziantep 27310, Türkiye.
Yıldız TutuncuDepartment of Immunology, Koc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University Istanbul, Istanbul 34010, Türkiye.ORCID 0000-0002-3905-6429
Oya ItilDepartment of Pulmonary Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir 35340, Türkiye.
Hasan BayramKoc University Research Center for Translational Medicine (KUTTAM), School of Medicine, Koc University, Istanbul 34010, Türkiye.ORCID 0000-0002-5236-766X

Funding

Turkish Thoracic Society 356/22.05.2021
6 · The paper itself

Abstract

The multisystemic effects of COVID-19 may continue for a longer time period following the acute phase, depending on the severity of the disease. However, long-term systemic transcriptomic changes associated with COVID-19 disease and the impact of disease severity are not fully understood. We aimed to investigate the impact of COVID-19 and its severity on transcriptomic alterations in peripheral blood mononuclear cells (PBMCs) following 1 year of the disease. PBMCs were isolated from the peripheral blood of healthy control donors who did not have COVID-19 (C;

Indexed as

COVID-19Gene Expression ProfilingLeukocytes, MononuclearSARS-CoV-2TranscriptomeAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPneumoniaRNA, Long NoncodingSeverity of Illness IndexRNA, Long NoncodingCOVID-19inflammatory responseslong-term effectsperipheral blood mononuclear cells (PBMC)pneumoniatranscriptomic analysis

Identifiers

PMID39205185
PMCPMC11358892

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.