Evidence map›Paper›PMID 39205265›Full record

ReviewViruses2024

Oncoviral Infections and Small Extracellular Vesicles.

Łukasz Ważny, Theresa L Whiteside, Monika Pietrowska

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Łukasz WażnyMaria Sklodowska-Curie National Research Institute of Oncology, 44-102 Gliwice, Poland.ORCID 0009-0002-1490-2219
Theresa L WhitesideUPMC Hillman Cancer Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA.ORCID 0000-0001-7316-6181
Monika PietrowskaMaria Sklodowska-Curie National Research Institute of Oncology, 44-102 Gliwice, Poland.

Funding

Small extracellular vesicles as biomarkers of prognosis and response to therapy in head and neck cancerR01DE031299 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Brenda B. Diergaarde, Theresa L. Whiteside · 2023 to 2026
$2.9M
NIDCR NIH HHS R01 DE031299NIH HHS 1R01DE031299-01A1
6 · The paper itself

Abstract

Small extracellular vesicles (sEV) are small membrane-bound nanovesicles with a size range below 200 nm that are released by all types of cells. sEV carry a diverse cargo of proteins, lipids, glycans, and nucleic acids that mimic the content of producer cells. sEV mediate intercellular communication and play a key role in a broad variety of physiological and pathological conditions. Recently, numerous reports have emerged examining the role of sEV in viral infections. A significant number of similarities in the sEV biogenesis pathways and the replication cycles of viruses suggest that sEV might influence the course of viral infections in diverse ways. Besides directly modulating virus propagation by transporting the viral cargo (complete virions, proteins, RNA, and DNA), sEV can also modify the host antiviral response and increase the susceptibility of cells to infection. The network of mutual interactions is particularly complex in the case of oncogenic viruses, deserving special consideration because of its significance in cancer progression. This review summarizes the current knowledge of interactions between sEV and oncogenic viruses, focusing on sEV abilities to modulate the carcinogenic properties of oncoviruses.

Indexed as

Extracellular VesiclesAnimalsHost-Pathogen InteractionsHumansNeoplasmsOncogenic VirusesTumor Virus InfectionsVirus Replicationexosomesoncovirusessmall extracellular vesicles (sEV)viral infections

Identifiers

PMID39205265
PMCPMC11359865

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.