Evidence mapPaperPMID 39209476Full record

ReviewThe European respiratory journal2024

Treatment algorithm for pulmonary arterial hypertension.

Kelly M Chin, Sean P Gaine, Christian Gerges, Zhi-Cheng Jing, Stephen C Mathai, Yuichi Tamura, Vallerie V McLaughlin, Olivier Sitbon

Abstract readReview
In one paragraph

Review in The European respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 5 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. International Liver Transplantation Society practice guideline update on portopulmonary hypertension.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Guideline
  3. Parenteral treprostinil in paediatric pulmonary arterial hypertension: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  4. Management of pulmonary arterial hypertension in systemic sclerosis: from classical treatments to new horizons.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  5. Pooled it
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  20. The right time, the right cell: the potential for precision senotherapy in pulmonary arterial hypertension.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review

71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Kelly M ChinDivision of Pulmonary and Critical Care Medicine, UT Southwestern, Dallas, TX, USA.
Sean P GaineDepartment of Respiratory Medicine, National Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin, Ireland.
Christian GergesDivision of Cardiology, Department of Internal Medicine II, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-6777-0996
Zhi-Cheng JingDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0003-0493-0929
Stephen C MathaiDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-3188-7209
Yuichi TamuraPulmonary Hypertension Center, International University of Health and Welfare Mita Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0002-4437-8019
Vallerie V McLaughlinDivision of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA vmclaugh@med.umich.edu.
Olivier SitbonDepartment of Respiratory Medicine, Hôpital Bicêtre (AP-HP), Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-1942-1951

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial hypertension leads to significant impairment in haemodynamics, right heart function, exercise capacity, quality of life and survival. Current therapies have mechanisms of action involving signalling

Indexed as

AlgorithmsAntihypertensive AgentsLung TransplantationPulmonary Arterial HypertensionDrug Therapy, CombinationEndothelin-1EpoprostenolHemodynamicsHumansHypertension, PulmonaryNitric OxideQuality of LifeAntihypertensive AgentsEndothelin-1EpoprostenolNitric Oxide

Identifiers

PMID39209476
PMCPMC11525349

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.