Evidence map›Paper›PMID 39212835›Full record

ReviewTranslational stroke research2025

Prevention of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage-Summary of Existing Clinical Evidence.

Margaux Miller, Priya Thappa, Hemant Bhagat, Michael Veldeman, Redi Rahmani

Abstract readReview
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In one paragraph

Review in Translational stroke research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Margaux MillerBarrow Neurological Institute, 2910 N 3rd Avenue, Phoenix, AZ, 85013, USA.
Priya ThappaAll India Institute of Medical Sciences, Nagpur, India.
Hemant BhagatDepartment of Anesthesia and Intensive Care, Chandigarh, India.
Michael VeldemanDepartment of Neurosurgery, RWTH Aachen University Hospital, Aachen, Germany.
Redi RahmaniBarrow Neurological Institute, 2910 N 3rd Avenue, Phoenix, AZ, 85013, USA. Redi.Rahmani@barrowbrainandspine.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2023 International Subarachnoid Hemorrhage Conference identified a need to provide an up-to-date review on prevention methods for delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage and highlight areas for future research. A PubMed search was conducted for key factors contributing to development of delayed cerebral ischemia: anesthetics, antithrombotics, cerebrospinal fluid (CSF) diversion, hemodynamic, endovascular, and medical management. It was found that there is still a need for prospective studies analyzing the best methods for anesthetics and antithrombotics, though inhaled anesthetics and antiplatelets were found to have some advantages. Lumbar drains should increasingly be considered the first line of CSF diversion when applicable. Finally, maintaining euvolemia before and during vasospasm is recommended as there is no evidence supporting prophylactic spasmolysis or angioplasty. There is accumulating observational evidence, however, that intra-arterial spasmolysis with refractory DCI might be beneficial in patients not responding to induced hypertension. Nimodipine remains the medical therapy with the most support for prevention.

Indexed as

Brain IschemiaSubarachnoid HemorrhageHumansVasospasm, IntracranialAnestheticsAneurysmal subarachnoid hemorrhageAntithromboticCerebrospinal fluid diversionDelayed cerebral ischemiaHemodynamics and endovascular management

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.