Evidence map›Paper›PMID 39214974›Full record

ArticleNature communications2024

Self-immolative poly(thiocarbamate) with localized H

Qingyu Zong, Jun Li, Qing Xu, Ye Liu, Kewei Wang, Youyong Yuan

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Self-Immolative Polyion Complexes.Macromolecular rapid communications · 2025
    Article
  7. Base-Catalyzed Pathway Towards Isocyanate Derivatives of Silsesquioxanes.International journal of molecular sciences · 2025
    Article
  8. A Needle-Like HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qingyu Zong *School of Medicine, South China University of Technology, Guangzhou, 510006, China.
Jun Li *National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou, China.
Qing XuSchool of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou, China.
Ye LiuSchool of Medicine, South China University of Technology, Guangzhou, 510006, China.
Kewei WangSchool of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou, China.
Youyong YuanNational Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou, China. yuanyy@scut.edu.cn.ORCID 0000-0003-2784-3780

Funding

National Natural Science Foundation of China (National Science Foundation of China) 52073101
6 · The paper itself

Abstract

Hydrogen sulfide is essential in numerous physiological and pathological processes and has emerged as a promising cancer imaging and signaling molecule and a potentially versatile therapeutic agent. However, the endogenous levels of hydrogen sulfide remain insufficient to perform its biological functions, and thus, developing novel strategies that amplify hydrogen sulfide signals at lesion sites is of increasing interest. In this work, a nanoplatform (SNP) based on hydrogen sulfide-responsive self-immolative poly(thiocarbamate) with localized hydrogen sulfide signal amplification capability is developed to encapsulate a hydrogen sulfide-responsive fluorescent probe (e.g., hemicyanine dye; p-Cy) or an anticancer prodrug (e.g., doxorubicin; p-DOX) to form a nanoprobe (SNP

Indexed as

DoxorubicinHydrogen SulfideAnimalsAntineoplastic AgentsBreast NeoplasmsCell Line, TumorFemaleFluorescent DyesHumansMiceMice, Inbred BALB CMice, NudeNanoparticlesNeoplasmsOptical ImagingProdrugsAntineoplastic AgentsDoxorubicinFluorescent DyesHydrogen SulfideProdrugs

Identifiers

PMID39214974
PMCPMC11364784

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.