Evidence mapPaperPMID 39215294Full record

ArticleBMC endocrine disorders2024

Time to first optimal glycemic control and its predictors among adult type 2 diabetes patients in Amhara Regional State comprehensive specialized hospitals, Northwest Ethiopia.

Sintayehu Chalie, Atsede Alle Ewunetie, Moges Agazhe Assemie, Atalay Liknaw, Friehiwot Molla, Animut Takele Telayneh, Bekalu Endalew

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Article in BMC endocrine disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Sintayehu ChalieDega Damot District Health Office, West Gojjam Zone, Amhara Region, Feresbet, Ethiopia.
Atsede Alle EwunetieDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Moges Agazhe AssemieDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Atalay LiknawDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Friehiwot MollaDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Animut Takele TelaynehDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Bekalu EndalewDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia. bekiehsm@gmail.com.

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6 · The paper itself

Abstract

backgroundInadequate glycemic management in type 2 diabetes Mellitus patients is a serious public health issue and a key risk factor for progression as well as diabetes-related complications. The main therapeutic goal of preventing organ damage and other problems caused by diabetes is glycemic control. Knowing when to modify glycemic control in type 2 diabetes Mellitus is crucial for avoiding complications and early drug intensifications.

methodsAn institutional based retrospective follow-up study was undertaken among 514 eligible adult diabetes patients in Amhara region Comprehensive Specialized Hospitals, Northwest Ethiopia, from January 2017 to January 2022. Simple random sampling technique was used to select study participants. The Kaplan Meier curve was used to assess the survival status of categorical variables, and the log-rank test was used to compare them. The cox proportional hazard model was fitted to identify the predictors of time to first optimal glycemic control. Variables with a p-value < 0.05 were considered to be statistically significance at 95% confidence interval.

resultsA total of 514 patient records (227 males and 287 females) were reviewed in this study. The median time to first optimal glycemic control among the study population was 8.4 months IQR (7.6-9.7). The predictors that affect the time to first optimal glycemic control were age group ((AHR = 0.63, 95% CI = 0.463, 0.859 for 50-59 years), (AHR = 0.638, 95% CI = 0.471, 0.865 for 60-69 years), and (AHR = 0.480, 95% CI = 0.298, 0.774 for > = 70 years)), diabetes neuropathy (AHR = 0.629, 95% CI = 0.441,0.900), hypertension (AHR = 0.667, 95% CI = 0.524, 0.848), dyslipidemia (AHR = 0.561, 95% CI = 0.410, 0.768), and cardiovascular disease (AHR = 0.681, 95% CI = 0.494, 0.938).

conclusionThe median time to initial optimal glycemic control in type 2 diabetes Mellitus patients in this study was short. Age between 50 and 59 years and 60-69, diabetes neuropathy, hypertension, dyslipidemia, and cardiovascular disease were predictor's of time to first glycemic control. Therefore, health care providers should pay extra attention for patients who are aged and who have complications or co-morbidities.

Indexed as

Diabetes Mellitus, Type 2Glycemic ControlAdultAgedBlood GlucoseEthiopiaFemaleFollow-Up StudiesGlycated HemoglobinHospitals, SpecialHumansHypoglycemic AgentsMaleMiddle AgedPrognosisRetrospective StudiesBlood GlucoseGlycated HemoglobinHypoglycemic AgentsAdultsEthiopiaFirst optimal glycemic controlType 2 diabetes mellitus

Identifiers

PMID39215294
PMCPMC11363452

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