Evidence map›Paper›PMID 39215362›Full record

ReviewChinese medicine2024

Astragali radix (Huangqi): a time-honored nourishing herbal medicine.

Yuyu Zhang, Zhejie Chen, Liping Chen, Qin Dong, Dong-Hua Yang, Qi Zhang, Jing Zeng, Yang Wang, Xiao Liu, Yuan Cui and 6 more

Abstract readReview
In one paragraph

Review in Chinese medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Formononetin attenuates glucocorticoid-induced osteoporosis via multiple osteoimmunological pathways: evidence from zebrafish and network pharmacology.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Advancement ofChinese herbal medicines · 2026
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Labile carbon drives synergistic improvements inFrontiers in plant science · 2026
    Article
  17. Molecular medicine reports · 2025
    Review
  18. Article
  19. Article
  20. Beyond Traditional Use: The Scientific Evidence for the Role ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yuyu Zhang *School of Food and Bioengineering, Xihua University, Chengdu, 610039, China.
Zhejie Chen *Institute of Molecular Medicine (IMM), Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Liping ChenSchool of Comprehensive Health Management, Xihua University, Chengdu, 610039, China.
Qin DongSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China.
Dong-Hua YangNew York College of Traditional Chinese Medicine, Mineola, NY, 11501, USA.
Qi ZhangPengzhou Hospital of Traditional Chinese Medicine, Pengzhou, 611930, China.
Jing ZengSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China.
Yang WangSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China.
Xiao LiuSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China.
Yuan CuiSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China.
Minglong LiSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China.
Xiao LuoChengdu Institute for Drug Control, NMPA Key Laboratory for Quality Monitoring and Evaluation of Traditional Chinese Medicine, Chengdu, 610045, China.
Chongjian ZhouHuBei Guizhenyuan Chinese Herbal Medicine Co.Ltd., Hong'an, 438400, China.
Mingzhu YeSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China.
Ling LiSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China. 892214894@qq.com.ORCID http://orcid.org/0009-0002-6043-2254
Yuxin HeSchool of Food and Bioengineering, Xihua University, Chengdu, 610039, China. 524225843@qq.com.

Funding

Central Nervous System Drug Key Laboratory of Sichuan Province 230016-01SZChina Postdoctoral Science Foundation 2023M732316Higher Education Talent Training Quality and Teaching Reform Project of Sichuan Province xjjg2021096Key Research and Development Project of Liangshan Prefecture 23ZDYF0177National Key R&D Program of China 2023YFC3504100the Open Research Fund of Chengdu University of Traditional Chinese Medicine State Key Laboratory of Southwestern Chinese Medicine Resources SKLTCM2022013Xihua University Science and Technology Innovation Competition Project for Postgraduate Students YK20240253
6 · The paper itself

Abstract

Astragali radix (AR, namded Huangqi in Chinese) is the dried root of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or Astragalus membranaceus (Fisch.) Bge. As a widely used ethnomedicine, the biological activities of AR include immunomodulatory, anti-hyperglycemic, anti-oxidant, anti-aging, anti-inflammatory, anti-viral, anti-tumor, cardioprotective, and anti-diabetic effects, with minimum side effects. Currently, it is known that polysaccharides, saponins, and flavonoids are the indispensable components of AR. In this review, we will elaborate the research advancements of AR on ethnobotany, ethnopharmacological practices, phytochemicals, pharmacological activities, clinical uses, quality control, production developments, and toxicology. The information is expected to assist clinicians and scientists in developing useful therapeutic medicines with minimal systemic side effects.

Indexed as

Astragalus membranaceusEthnobotanyEthnopharmacological usesHuangqiNatural products

Identifiers

PMID39215362
PMCPMC11363671

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.