Evidence map›Paper›PMID 39215892›Full record

ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2025

Ballota hirsuta essential oil as a potential multitarget agent against Leishmania parasite: in vitro and in silico studies.

Rym Essid, Sarra Kefi, Bilel Damergi, Ghassen Abid, Nadia Fares, Selim Jallouli, Olfa Tabbene, Ferid Limam

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Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rym Essid *Laboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopole, BP 901, 2050, Hammam-Lif, Tunisia. essidrym@hotmail.com.
Sarra Kefi *Laboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopole, BP 901, 2050, Hammam-Lif, Tunisia.
Bilel DamergiLaboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopole, BP 901, 2050, Hammam-Lif, Tunisia.
Ghassen AbidLaboratory of Legumes and Sustainable Agro-Systems, Centre of Biotechnology of Borj Cedria, Hammam-Lif, Tunisia.
Nadia FaresLaboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopole, BP 901, 2050, Hammam-Lif, Tunisia.
Selim JallouliLaboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopole, BP 901, 2050, Hammam-Lif, Tunisia.
Olfa TabbeneLaboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopole, BP 901, 2050, Hammam-Lif, Tunisia.
Ferid LimamLaboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopole, BP 901, 2050, Hammam-Lif, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, we assessed the antioxidant and antileishmanial potential from fresh leaves of Ballota (B.) hirsuta essential oil (EO). The GC-MS analysis of B. hirsuta EO revealed that spathulenol and germacrene D were the main components accounting for 26.03% and 19.64% of the total EO, respectively. B. hirsuta EO possesses moderate antioxidant activity, both in neutralizing DPPH radicals and in inhibiting β-carotene bleaching. In addition, it exhibits both high antileishmanial activity and selectivity towards the promastigote and amastigote forms. Specifically, B. hirsuta EO showed an IC

Indexed as

Antiprotozoal AgentsLeishmaniaLeishmania infantumOils, VolatileAntioxidantsGas Chromatography-Mass SpectrometryInhibitory Concentration 50Molecular Docking SimulationPlant LeavesSesquiterpenes, GermacraneAntioxidantsAntiprotozoal AgentsOils, VolatileSesquiterpenes, GermacraneAntioxidant activityBallota hirsuta EOCytotoxicityLeishmanicidal activitySterol pathwayThiol pathway

Identifiers

PMID39215892

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.