Evidence map›Paper›PMID 39216685›Full record

ArticleContemporary clinical trials2024

EXpanding Technology-Enabled, Nurse-Delivered Chronic Disease Care (EXTEND): Protocol and Baseline Data for a Randomized Trial.

Jashalynn German, Qing Yang, Daniel Hatch, Allison Lewinski, Hayden B Bosworth, Brystana G Kaufman, Ranee Chatterjee, Gina Pennington, Doreen Matters, Donghwan Lee and 12 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04587336 (Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04587336 completednot on this map

Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes (TARDIS) - Survey & Qualitative Interview

TypeobservationalSponsorVA Office of Research and DevelopmentRan2020 to 2025Enrolled225ConditionsDiabetes, Diabetes Distress, Self-Management, VeteranArmsCognitive Interview, Baseline Survey, Qualitative Interviews
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Jashalynn GermanDivision of Endocrinology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Qing YangSchool of Nursing, Duke University, Durham, NC, USA.
Daniel HatchSchool of Nursing, Duke University, Durham, NC, USA.
Allison LewinskiSchool of Nursing, Duke University, Durham, NC, USA; Durham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, Durham, NC, United States of America.
Hayden B BosworthDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC, USA; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.
Brystana G KaufmanDurham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, Durham, NC, United States of America; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA; Duke-Margolis Center for Health Policy, Duke University, Durham, NC, USA.
Ranee ChatterjeeDivision of General Internal Medicine, Department of Medicine, Duke University, Durham, NC 27713, USA.
Gina PenningtonSchool of Nursing, Duke University, Durham, NC, USA.
Doreen MattersSchool of Nursing, Duke University, Durham, NC, USA.
Donghwan LeeSchool of Nursing, Duke University, Durham, NC, USA.
Diana UrlichichSchool of Nursing, Duke University, Durham, NC, USA.
Sarah KokosaDepartment of Pharmacy, Duke University, Durham, NC, USA.
Holly CanuppDepartment of Pharmacy, Duke University, Durham, NC, USA.
Patrick GregoryDepartment of Pharmacy, Duke University, Durham, NC, USA.
Cindy Leslie RobersonDepartment of Pharmacy, Duke University, Durham, NC, USA.
Benjamin SmithDepartment of Pharmacy, Duke University, Durham, NC, USA.
Sherry HuberDuke Office of Clinical Research, Duke University School of Medicine, Durham, NC, USA.
Katheryn DoukellisDuke Office of Clinical Research, Duke University School of Medicine, Durham, NC, USA.
Tammi DealDivision of General Internal Medicine, Department of Medicine, Duke University, Durham, NC 27713, USA.
Rose BurnsDuke Office of Clinical Research, Duke University School of Medicine, Durham, NC, USA.
Matthew J CrowleyDivision of Endocrinology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA; Durham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, Durham, NC, United States of America.
Ryan J ShawSchool of Nursing, Duke University, Durham, NC, USA. Electronic address: ryan.shaw@duke.edu.

Funding

EXpanding Technology-Enabled, Nurse-Delivered Chronic Disease Care (EXTEND)R01NR019594 · NINR · DUKE UNIVERSITY · 2023 to 2025
$2.0M
Endocrinology and Metabolism Training ProgramT32DK007012 · DUKE UNIVERSITY · 1986 to 2025
$1.3M
HSRD VA CIN 13-410NCATS NIH HHS UL1 TR002553NIDDK NIH HHS T32 DK007012NINR NIH HHS R01 NR019594
6 · The paper itself

Abstract

backgroundApproximately 10-15 % of individuals with type 2 diabetes have persistently poorly-controlled diabetes mellitus (PPDM) despite receiving available care, and frequently have comorbid hypertension. Mobile monitoring-enabled telehealth has the potential to improve outcomes in treatment-resistant chronic disease by supporting self-management and facilitating patient-clinician contact but must be designed in a manner amenable to real-world use.

methodsExpanding Technology-Enabled, Nurse-Delivered Chronic Disease Care (EXTEND) is an ongoing randomized trial comparing two 12-month interventions for comorbid PPDM and hypertension: 1) EXTEND, a mobile monitoring-enabled self-management intervention; and 2) EXTEND Plus, a comprehensive, nurse-delivered telehealth program incorporating mobile monitoring, self-management support, and pharmacist-supported medication management. Both arms leverage a novel platform that uses existing technological infrastructure to enable transmission of patient-generated health data into the electronic health record. The primary study outcome is difference in HbA1c change from baseline to 12 months. Secondary outcomes include blood pressure, weight, implementation barriers/facilitators, and costs.

resultsEnrollment concluded in June 2023 following randomization of 220 patients. Baseline characteristics are similar between arms; mean age is 54.5 years, and the cohort is predominantly female (63.6 %) and Black (68.2 %), with a baseline HbA1c of 9.81 %.

conclusionThe EXTEND trial is evaluating two mobile monitoring-enabled telehealth approaches that seek to improve outcomes for patients with PPDM and hypertension. Critically, these approaches are designed around existing infrastructure, so may be amenable to implementation and scaling. This study will promote real-world use of telehealth to maximize benefits for those with high-risk chronic disease.

Indexed as

Diabetes Mellitus, Type 2Glycated HemoglobinHypertensionTelemedicineAdultAgedBlood PressureChronic DiseaseFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicSelf-ManagementGlycated HemoglobinChronic diseaseDiabetes mellitusDigital healthHypertensionTelemedicine

Identifiers

PMID39216685
PMCPMC11531378

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.