ReviewClinical hypertension2024
Obesity and hypertension in children and adolescents.
Review in Clinical hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Beyond genetics: how environmental stressors drive pediatric hypertension risk.Pediatric nephrology (Berlin, Germany) · 2026Review
- A study of body composition, muscle strength, and arterial stiffness in adolescents with primary and secondary hypertension.Pediatric nephrology (Berlin, Germany) · 2026Article
- Article
- Associations of health parameters at 16 years of age with structural knee MRI findings at 33 years of age in a general population-based birth cohort.Osteoarthritis and cartilage open · 2026Article
- Anti-obesity medications in children and adolescents: blood pressure and chronic kidney disease implications.Pediatric nephrology (Berlin, Germany) · 2026Review
- Article
- Prevalence of hypertension in children evaluated for headache: The role of body mass index.Medicine · 2026Article
- A Growing Burden: Obesity's Impact on Cardiometabolic Disease Risk in Children and Adolescents.Current cardiology reports · 2026Review
- Serum S100β and neuron-specific enolase correlate with obesity parameters in Mexican children.International journal of obesity (2005) · 2026Article
- Trends and risk factors of hypertension in US Children and Adolescents, 1999-2023.Journal of human hypertension · 2026Observational
- Obesity and Resting Metabolic Rate Assessed by Indirect Calorimetry in Pediatric Patients from Northeastern Romania.Diagnostics (Basel, Switzerland) · 2026Article
- Elevated Blood Pressure and Risk Factors in 19-Year-Olds in Serbia: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Nutritional and behavioral determinants of overweight and obesity among school-aged children in Shandong Province, China: evidence from a large-scale cross-sectional study.Frontiers in nutrition · 2026Article
- Associations of the Triglyceride-Glucose Index and Body Fat Composition with Blood Pressure in Children and Adolescents.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- Obesity‑related kidney disease: a review on ultrasound applications.Italian journal of pediatrics · 2025Review
- Oxidative Stress and Endothelial Dysfunction: The Pathogenesis of Pediatric Hypertension.International journal of molecular sciences · 2025Review
- The Role of Nutraceuticals and Probiotics in Addition to Lifestyle Intervention in the Management of Childhood Obesity-Part 2: Comorbidities.Nutrients · 2025Review
- Different risk factors for elevated blood pressure according to abdominal obesity in overweight children and adolescents.BMC pediatrics · 2025Article
- Prevalence of and Factors Associated with Hypertension in Children and Adolescents as Observed by German Pediatricians-A Case-Control Study.Children (Basel, Switzerland) · 2025Article
- Evaluating the Influence of Weight Status and Gender on Moderate to Vigorous Physical Activity and Sedentary Time in Physical Education Lessons: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As childhood obesity rates increase worldwide, the prevalence of obesity-related hypertension is also on the rise. Obesity has been identified as a significant risk factor for hypertension in this age group. National Health Surveys and meta-analyses show increasing trends in obesity and pediatric hypertension in obese children. The diagnosis of hypertension in children involves percentiles relative to age, sex, and height, unlike in adults, where absolute values are considered. Elevated blood pressure (BP) in childhood is consistently associated with cardiovascular disease in adulthood, emphasizing the need for early detection and intervention. The pathogenesis of hypertension in obesity involves multiple factors, including increased sympathetic nervous system activity, activation of the renin-angiotensin-aldosterone system (RAAS), and renal compression due to fat accumulation. Obesity disrupts normal RAAS suppression and contributes to impaired pressure natriuresis and sodium retention, which are critical factors in the development of hypertension. Risk factors for hypertension in obesity include degree, duration, and distribution of obesity, patient age, hormonal changes during puberty, high-sodium diet, sedentary lifestyle, and socioeconomic status. Treatment involves lifestyle changes, with weight loss being crucial to lowering BP. Medications such as angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers may be considered first, and surgical approaches may be an option for severe obesity, requiring tailored antihypertensive medications that consider individual pathophysiology to avoid exacerbating insulin resistance and dyslipidemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.