Evidence map›Paper›PMID 39217592›Full record

SynthesisEuropean child & adolescent psychiatry2025

Prevalence of mental disorders among family members of individuals on the autism spectrum: systematic review and meta-analysis.

Daniel H Lins-Silva, Igor D Bandeira, Daniela Faria-Guimarães, Ingrid Dorea-Bandeira, Arthur Tolentino, Ângela Miranda-Scippa, Daniel F Hermens, Rita Lucena

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European child & adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Quality of life in caregivers of toddlers with autism features.Research in developmental disabilities · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel H Lins-Silva *Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Brazil.
Igor D Bandeira *Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, USA. igordbandeira@gmail.com.
Daniela Faria-GuimarãesFaculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Brazil.
Ingrid Dorea-BandeiraFaculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Brazil.
Arthur TolentinoDepartamento de Psicologia Médica e Psiquiatria, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, Brazil.
Ângela Miranda-ScippaDepartamento de Neurociências e Saúde Mental, Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Brazil.
Daniel F HermensSunshine Coast Mind and Neuroscience Thompson Institute, University of the Sunshine Coast, Birtinya, Australia.
Rita LucenaDepartamento de Neurociências e Saúde Mental, Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parenting a child on the autism spectrum presents particular challenges that can lead to increased stress, anxiety, and depression among family members. Therefore, we aimed to investigate the prevalence of mental disorders in first-degree relatives of individuals on the autism spectrum. This article adheres to the Preferred Reporting Items for Systematic Review and Meta-Analyses Protocols (PRISMA-P) guidelines, including studies indexed in PubMed/Medline, Embase, PsycINFO, Biblioteca Virtual em Saúde (BVS), and SciELO. Nineteen articles met eligibility criteria for the systematic review. Using a random-effects model (N = 93,876), we found a pooled prevalence of affective disorders of 13% in mothers of people on the autism spectrum (95% CI 7-21%; I

Indexed as

Autism Spectrum DisorderFamilyMental DisordersChildHumansPrevalenceAffective disordersAutism spectrum disorderMajor depressive disorderMental disordersParentsSiblings

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.