Evidence map›Paper›PMID 39221931›Full record

ReviewCurrent opinion in endocrinology, diabetes, and obesity2024

Time to cycle regularity and health risks.

Amna Naveed, Rachel Whooten

Abstract readReview
In one paragraph

Review in Current opinion in endocrinology, diabetes, and obesity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amna NaveedDivision of Pediatric Endocrinology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Rachel Whooten

Funding

Investigating the impact of physical activity in modulating PCOS risk among peripubertal femalesK23DK131322 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Rachel Whooten · 2023 to 2026
$771k
NIDDK NIH HHS K23 DK131322
6 · The paper itself

Abstract

purpose of reviewAdolescents often have irregular menstrual cycles after menarche until the reproductive axis fully matures. This review explores how menstrual regularity is established and the health risks associated with prolonged time to cycle regularity in adolescents. RECENT

findingsCross-sectional studies show an association between prolonged time to cycle regularity in adolescents and increased risks for ongoing menstrual dysfunction, cardiometabolic disorders, cancers, and overall mortality. Importantly, some of these cardiometabolic associations are independent of PCOS status. SUMMARY: The menstrual cycle can be used as a vital sign for assessing overall health. While further longitudinal studies are needed to establish causal relationships, these findings highlight a crucial window for early intervention in adolescents with prolonged time to cycle regularity to mitigate future risks.

Indexed as

Menstrual CycleMenstruation DisturbancesAdolescentCardiovascular DiseasesFemaleHumansNeoplasmsPolycystic Ovary SyndromeRisk FactorsTime Factors

Identifiers

PMID39221931
PMCPMC12459127

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.