Evidence map›Paper›PMID 39222193›Full record

SynthesisObesity surgery2024

The Effect of Bariatric Surgery on PAI-1 Levels: A Systematic Review and Meta-analysis.

Tannaz Jamialahamdi, Elaheh Mirhadi, Wael Almahmeed, Vasily N Sukhorukov, Ali H Eid, Sepideh Salehabadi, Amirhossein Sahebkar

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Tannaz JamialahamdiPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Elaheh MirhadiSchool of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Wael AlmahmeedHeart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Vasily N SukhorukovInstitute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, Moscow, 125315, Russia.
Ali H EidDepartment of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha, Qatar.
Sepideh SalehabadiMedical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Amirhossein SahebkarCenter for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India. amir_saheb2000@yahoo.com.ORCID 0000-0002-8656-1444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this meta-analysis was to determine the effect of bariatric surgery on circulating PAI-1. The meta-analysis was provided by comprehensive meta-analysis (CMA) V4 software. Meta-analysis of 33 studies showed a significant decrease in circulating PAI-1 after bariatric surgery (p < 0.001). A significant reduction was observed for two types of surgery) (p < 0.001 for LSG and p < 0.001 for RYGB). Furthermore, there was a significant change in circulating PAI-1 based on the follow-up duration (p < 0.001 for follow-up < 12 months and p < 0.001 for follow-up ≥ 12). We showed that bariatric surgery changed PAI-1 level significantly and changes in BMI after surgery were not related to PAI-1 alteration. Furthermore, this result was consistent based on follow-up duration and type of surgery.

Indexed as

Bariatric SurgeryObesity, MorbidPlasminogen Activator Inhibitor 1Body Mass IndexHumansTreatment OutcomeWeight LossPlasminogen Activator Inhibitor 1SERPINE1 protein, humanFibrinolysisInflammationMetabolic surgeryObesityPAI-1

Identifiers

PMID39222193

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.