Evidence map›Paper›PMID 39222217›Full record

Trial reportExperimental physiology2024

Digoxin and exercise effects on skeletal muscle Na

Michael J McKenna, Xiaofei Gong, Aaron C Petersen, Simon Sostaric, Craig A Goodman, Andrew Garnham, Tai-Juan Aw, Collene H Steward, Kate T Murphy, Kate A Carey and 3 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Experimental physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Michael J McKennaInstitute for Health and Sport, Victoria University, Melbourne, Australia.ORCID https://orcid.org/0000-0001-9998-0093
Xiaofei GongInstitute for Health and Sport, Victoria University, Melbourne, Australia.
Aaron C PetersenInstitute for Health and Sport, Victoria University, Melbourne, Australia.ORCID https://orcid.org/0000-0003-1508-748X
Simon SostaricInstitute for Health and Sport, Victoria University, Melbourne, Australia.ORCID https://orcid.org/0000-0003-0701-0992
Craig A GoodmanInstitute for Health and Sport, Victoria University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-5874-7743
Andrew GarnhamInstitute for Health and Sport, Victoria University, Melbourne, Australia.ORCID https://orcid.org/0000-0001-8068-9300
Tai-Juan AwDepartment of Epidemiology and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Australia.ORCID https://orcid.org/0000-0001-8363-9499
Collene H StewardInstitute for Health and Sport, Victoria University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-7903-0346
Kate T MurphyInstitute for Health and Sport, Victoria University, Melbourne, Australia.ORCID https://orcid.org/0000-0003-1993-4367
Kate A CareyInstitute for Breathing and Sleep, Melbourne, Australia.ORCID https://orcid.org/0000-0002-5748-0768
Henry Krum *Department of Epidemiology and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Australia.ORCID https://orcid.org/0000-0002-0655-3015
Rodney J SnowInstitute of Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-4796-6916
David Cameron-SmithDepartment of Nutrition, Singapore Institute of Food and Biotechnology Innovation (SIFBI), Singapore, Singapore.ORCID https://orcid.org/0000-0002-0144-5816

Funding

National Health and Medical Research Council of Australia 256603
6 · The paper itself

Abstract

In muscle, digoxin inhibits Na

Indexed as

Cross-Over StudiesDigoxinExerciseMuscle, SkeletalSodium-Potassium-Exchanging ATPaseAdultDouble-Blind MethodFemaleGene ExpressionHumansIsoenzymesMaleProtein IsoformsRNA, MessengerYoung AdultDigoxinIsoenzymesProtein IsoformsRNA, MessengerSodium-Potassium-Exchanging ATPasedigoxinexercisemRNANa+,K+‐pumpskeletal muscle

Identifiers

PMID39222217
PMCPMC11522823

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.