Evidence map›Paper›PMID 39223249›Full record

ArticleCommunications biology2024

Activated tissue-resident macrophages contribute to hair cell insults in noise-induced hearing loss in mice.

Jing Pan, Kaiye Wang, Jiaxi Qu, Dongxiu Chen, Anning Chen, Yunyou You, Jie Tang, Hongzheng Zhang

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. CSNK1A1 Mediates Inner Ear Inflammation and Endolymphatic Hydrops in a Lipopolysaccharide-Induced Mouse Model.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
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  5. Recent Progress in Mechanism-Based Therapies forInternational journal of molecular sciences · 2026
    Review
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  17. CXFrontiers in immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing PanDepartment of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.ORCID 0000-0002-8203-8082
Kaiye WangDepartment of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Jiaxi QuDepartment of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Dongxiu ChenDepartment of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Anning ChenDepartment of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.ORCID 0000-0002-1707-4482
Yunyou YouDepartment of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Jie TangDepartment of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. jietang@smu.edu.cn.ORCID 0000-0001-7882-4462
Hongzheng ZhangDepartment of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. redtrue@smu.edu.cn.ORCID 0000-0001-8105-2256

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages serve as the primary immune cell population and assume a pivotal role in the immune response within the damaged cochleae. Yet, the origin and role of macrophages in response to noise exposure remain controversial. Here, we take advantage of Ccr2

Indexed as

Hearing Loss, Noise-InducedMacrophagesAnimalsCochleaHair Cells, AuditoryMacrophage ActivationMaleMiceMice, Inbred C57BLMice, TransgenicNoiseToll-Like Receptor 4Toll-Like Receptor 4

Identifiers

PMID39223249
PMCPMC11368919

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.