Evidence mapPaperPMID 39223291Full record

ArticleScientific reports2024

Activin A plays an essential role in migration and proliferation of hepatic stellate cells via Smad3 and calcium signaling.

Wei Zhang, Linjing Zhu, Fang Fang, Fenglin Zhang, Runnan Wang, Ke Yang, Yahui Liu, Xueling Cui

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei ZhangDepartment of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, 130021, Jilin, China.
Linjing ZhuDepartment of Genetics, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, China.
Fang FangDepartment of Genetics, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, China.
Fenglin ZhangDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, China.
Runnan WangDepartment of Genetics, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, China.
Ke YangInstitute of Applied Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, Anhui, China.
Yahui LiuDepartment of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, 130021, Jilin, China. yahui@jlu.edu.cn.
Xueling CuiDepartment of Genetics, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, China. cxl@jlu.edu.cn.

Funding

Foundation of Science and Technology Department of Jilin Province 20220402079GH and 20240404027ZP
6 · The paper itself

Abstract

Activin A and hepatic stellate cells (HSCs) are involved in tissue repair and fibrosis in liver injury. This study investigated the impact of activin A on HSC activation and migration. A microfluidic D

Indexed as

ActivinsCalcium SignalingCell MovementCell ProliferationHepatic Stellate CellsSmad3 ProteinAnimalsCell LineHumansMiceactivin AActivinsSmad3 ProteinActivin ACalcium signalingHepatic stellate cellsMigrationProliferationSmad3

Identifiers

PMID39223291
PMCPMC11369249

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.