Evidence map›Paper›PMID 39225213›Full record

ReviewCurrent radiopharmaceuticals2025

An Analysis of the Radiosensitiser Applications in the Biomedical Field.

Teng Sheng Lim, Irman Abdul Rahman, Aminah Umar, Norsyahidah Mohd Hidzir, Kenton Paul Arkill, Razinah Sharif, Mohd Anuar Jonet, Hur Munawar Kabir Mohd, Faizal Mohamed

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current radiopharmaceuticals, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Teng Sheng LimDepartment of Applied Physics, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor Darul Ehsan, Malaysia.
Irman Abdul RahmanDepartment of Applied Physics, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor Darul Ehsan, Malaysia.
Aminah UmarDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, 16424, Indonesia.
Norsyahidah Mohd HidzirDepartment of Applied Physics, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor Darul Ehsan, Malaysia.
Kenton Paul ArkillBiodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Razinah SharifNutritional Science Program and Centre for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, Kuala Lumpur, Malaysia.
Mohd Anuar JonetMalaysia Genome & Vaccine Institute, National Institute of Biotechnology Malaysia, Jalan Bangi, 43000, Kajang, Selangor, Malaysia.
Hur Munawar Kabir MohdDepartment of Applied Physics, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor Darul Ehsan, Malaysia.
Faizal MohamedDepartment of Applied Physics, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor Darul Ehsan, Malaysia.

Funding

Ministry of Higher Education Malaysia Fundamental Research Grant Scheme FRGS/1/2022/STG07/UKM/02/6Universiti Kebangsaan Malaysia (UKM) GUP-2018-060
6 · The paper itself

Abstract

backgroundVarious types of radiosensitisers have been introduced from the past until the present day for applications in the biomedical field. However, there is a lack of understanding and comparison between the various parameters introduced in addition to a lack of consensus among researchers on the optimal radiosensitiser for applications in the biomedical field.

objectiveThis review aimed to investigate the usage of radiosensitisers in the biomedical field, determine their important parameters, and suggest radiosensitisers with potential among the analysed radiosensitisers. RESULTS AND

conclusionThis review has discussed several parameters for radiosensitisers, including median lethal dose, cell survival, tumour size, cell viability, Dose Enhancement Factor (DEF), Reactive Oxygen Species (ROS) concentration, radiosensitiser production complexity, radiosensitiser administration technique, and radiosensitiser toxicity. General trends regarding the development of radiosensitisers, including the types, effectiveness, and their production complexity, have also been discussed within this review article.

Indexed as

NeoplasmsRadiation-Sensitizing AgentsAnimalsCell SurvivalHumansReactive Oxygen SpeciesRadiation-Sensitizing AgentsReactive Oxygen Speciesdose enhancementeffectiveness.gold nanoparticlesproduction complexityRadiosensitisertoxicity

Identifiers

PMID39225213

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.