Evidence map›Paper›PMID 39225418›Full record

ArticleLeukemia & lymphoma2024

Aplastic anemia in association with multiple myeloma: clinical and pathophysiological insights.

Tinatin Muradashvili, Yuxin Liu, Jennifer VanOudenhove, Sean X Gu, Diane S Krause, Francesca Montanari, Maximillian J Carlino, Rubia Mancuso, Jessica M Stempel, Stephanie Halene and 3 more

Abstract read
In one paragraph

Article in Leukemia & lymphoma, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tinatin MuradashviliDepartment of Internal Medicine, Yale School of Medicine, Waterbury, CT, USA.ORCID 0000-0002-6450-7199
Yuxin LiuSection of Hematology, Department of Internal Medicine, Dana-Farber Cancer Institute, Boston, MA, USA.
Jennifer VanOudenhoveSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Sean X GuDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Diane S KrauseDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Francesca MontanariSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Maximillian J CarlinoDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Rubia MancusoDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Jessica M StempelSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Stephanie HaleneSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-2737-9810
Amer M ZeidanSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-7017-8160
Nikolai A PodoltsevSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Natalia NeparidzeSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.

Funding

Yale Cooperative Hematology Specialized Core CenterU54DK106857 · NIDDK · YALE UNIVERSITY · PI JOHN HWA, Diane S Krause · 2015 to 2026
$9.7M
NIDDK NIH HHS U54 DK106857
6 · The paper itself

Abstract

We investigated immune cytopenia in multiple myeloma (MM) patients with concurrent acquired aplastic anemia (AA), focusing on three clinical cases treated with plasma cell-directed therapy. All three patients achieved partial response in MM and one patient experienced complete resolution of AA. Two patients had partial improvement in transfusion requirement but continued to suffer from severe AA, leading to immunosuppressive therapy (IST) with improvement of transfusion requirement in both patients.

Indexed as

Anemia, AplasticMultiple MyelomaAgedFemaleHumansMaleMiddle AgedTreatment Outcomeaplastic anemiacytopeniaimmuneMultiple myeloma

Identifiers

PMID39225418
PMCPMC13192466

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.