Evidence map›Paper›PMID 39227556›Full record

ArticleEuropean geriatric medicine2024

Prognostic impact of muscle ultrasound-guided diagnosis of sarcopenia in older adults with severe aortic stenosis.

Pablo Solla-Suarez, Pablo Avanzas, Marta Encuentra-Sopena, Marcel Almendárez, Áurea Álvarez-Abella, Rut Álvarez-Velasco, Fe Domingo-Lavandera, José Boga, Ana Coto-Montes, César Morís de la Tassa and 1 more

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In one paragraph

Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Pablo Solla-SuarezGeriatrics Department, Geriatrics Clinical Management Area, Monte Naranco Hospital-Central University Hospital of Asturias, Avenida Doctores Fernández Vega, 107, 33012, Oviedo, Asturias, Spain. pasosu@gmail.com.ORCID 0000-0003-0412-6578
Pablo AvanzasHealth Research Institute of Asturias, ISPA, Oviedo, Spain.
Marta Encuentra-SopenaGeriatrics Department, Geriatrics Clinical Management Area, Monte Naranco Hospital-Central University Hospital of Asturias, Avenida Doctores Fernández Vega, 107, 33012, Oviedo, Asturias, Spain.
Marcel AlmendárezHealth Research Institute of Asturias, ISPA, Oviedo, Spain.
Áurea Álvarez-AbellaGeriatrics Department, Geriatrics Clinical Management Area, Monte Naranco Hospital-Central University Hospital of Asturias, Avenida Doctores Fernández Vega, 107, 33012, Oviedo, Asturias, Spain.
Rut Álvarez-VelascoHealth Research Institute of Asturias, ISPA, Oviedo, Spain.
Fe Domingo-LavanderaGeriatrics Department, Geriatrics Clinical Management Area, Monte Naranco Hospital-Central University Hospital of Asturias, Avenida Doctores Fernández Vega, 107, 33012, Oviedo, Asturias, Spain.
José BogaHealth Research Institute of Asturias, ISPA, Oviedo, Spain.
Ana Coto-MontesHealth Research Institute of Asturias, ISPA, Oviedo, Spain.
César Morís de la TassaHealth Research Institute of Asturias, ISPA, Oviedo, Spain.
José Gutiérrez-RodríguezGeriatrics Department, Geriatrics Clinical Management Area, Monte Naranco Hospital-Central University Hospital of Asturias, Avenida Doctores Fernández Vega, 107, 33012, Oviedo, Asturias, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMuscle ultrasound is increasingly popular thanks to its advantages over other techniques. However, its usefulness in the diagnosis of sarcopenia in older adults with aortic stenosis (AS) has not been studied to date.

objectivesto analyze the prevalence of sarcopenia using muscle ultrasound and its impact on the health outcomes in older patients with AS.

methodsThe single-center FRESAS (FRailty-Evaluation-in-Severe-Aortic-Stenosis) registry was used to study patients over 75 years with severe AS susceptible to valve replacement. Sarcopenia was suspected in those individuals with diminished grip strength, and the diagnosis was confirmed in the presence of reduced ultrasound quadriceps muscle thickness, following the recommendations of the EWGSOP2 (European-Working-Group-on-Sarcopenia-in-Older-People). The primary composite endpoint was urgent hospital admission and mortality of cardiac cause 6 months after the diagnosis.

resultsOf the 150 patients studied, 55.3% were females, and only 17.3% were frail; the mean age was 83.4 years. Sarcopenia was diagnosed in 42 patients (28%). The overall survival rate at 6 months was 92%. The primary endpoint was recorded in 23.2% of the cases and was more frequent in the sarcopenic patients (33.3%) than in the non-sarcopenic individuals (17.6%) (p = 0.01). The regression analysis found that sarcopenia was associated with an increased risk of the primary endpoint (HR: 2.25; 95% CI 1.19-4.45; p = 0.02), adjusting for potential confounding factors.

conclusionsThe incidence of serious cardiac complications in older patients with sarcopenia and severe AS is significant. The present study describes a noninvasive, ultrasound-guided diagnostic technique that may prove efficient in its predictive capacity.

Indexed as

Aortic Valve StenosisSarcopeniaAgedAged, 80 and overFemaleGeriatric AssessmentHand StrengthHumansMalePrevalencePrognosisQuadriceps MuscleRegistriesUltrasonographyAortic valve replacementAortic valve stenosisFrailtySarcopeniaUltrasonography

Identifiers

PMID39227556

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.