Evidence map›Paper›PMID 39227932›Full record

ArticleInternational journal for equity in health2024

Temporal trends in lower extremity amputation in Middle East and North Africa (MENA) region: analysis of the GBD dataset 1990-2019.

Yazan A Al-Ajlouni, Mohamed Abouzid, Mohammad Tanashat, Ahmed Ahmed Basheer, Omar Al Ta'ani, Naciye Bilgin-Badur, Mohammad Islam

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Article in International journal for equity in health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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11citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yazan A Al-AjlouniDepartment of Rehabilitation, Montefiore Medical Center, Bronx, NY, USA. alajlouni.yazan@gmail.com.
Mohamed AbouzidDepartment of Physical Pharmacy and Pharmacokinetics, Faculty of Pharmacy, Poznan University of Medical Sciences, Rokietnicka 3 St, Poznan, 60-806, Poland.
Mohammad TanashatFaculty of Medicine, Yarmouk University, Irbid, Jordan.
Ahmed Ahmed BasheerDepartment of Physical Therapy for Musculoskeletal Disorders, Faculty of Physical Therapy, Beni Suef University, Beni Suef Governorate, Egypt.
Omar Al Ta'aniAllegheny Health Network, Pittsburgh, PA, USA.
Naciye Bilgin-BadurDepartment of Rehabilitation, Montefiore Medical Center, Bronx, NY, USA.
Mohammad IslamDepartment of Physical Medicine and Rehabilitation, Metropolitan Hospital, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLower extremity amputations (LEAs) significantly contribute to mortality and morbidity, often resulting from peripheral artery disease and diabetes mellitus (DM). Traumatic injuries also account for many LEAs. Despite the global burden, the epidemiology of LEAs, particularly in the Middle East and North Africa (MENA) region, remains underexplored. This study utilizes the Global Burden of Disease (GBD) dataset to analyze temporal trends in LEAs in the MENA region from 1990 to 2019.

methodsThe study utilized the 2019 GBD dataset, which includes estimates for incidence, prevalence, and disability-adjusted life-years (DALYs) across 369 diseases. Age-standardized incidence rates (ASIRs) for LEAs were extracted for 21 MENA countries. Trends were analyzed using percentage change calculations and Joinpoint regression to identify significant shifts in LEA rates over time.

resultsFrom 1990 to 2019, male LEA rates generally decreased, while female rates increased. Significant increases in LEA rates were observed in Syria, Yemen, and Afghanistan, correlating with periods of conflict and instability. Conversely, countries like Iraq, Palestine, Sudan, Lebanon, Iran, and Kuwait saw marked decreases. The study highlighted a complex interplay of socio-political factors, natural disasters, and chronic diseases like DM in shaping LEA trends across the region.

conclusionThe study reveals variable LEA trends in the MENA region, influenced by conflicts, natural disasters, and chronic diseases. These findings underscore the need for targeted public health interventions, improved healthcare access, and robust data collection systems to reduce the burden of LEAs and improve patient outcomes in the MENA region.

Indexed as

Amputation, SurgicalGlobal Burden of DiseaseLower ExtremityAdultAfrica, NorthernDisability-Adjusted Life YearsFemaleHumansIncidenceMaleMiddle AgedMiddle EastPrevalenceGlobal burden of diseaseHealthcare disparitiesLower extremity amputationMENA regionTemporal trends

Identifiers

PMID39227932
PMCPMC11370275

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.