Evidence map›Paper›PMID 39227976›Full record

ArticleBMC chemistry2024

Laser enhanced photothermal effect of silver nanoparticles synthesized by chemical and green method on Gram-positive and Gram-negative bacteria.

Elham M Mostafa, Y Badr, Marwa A Ramadan, Mohamed M M Hashem, Khaled Abo-El-Sooud, Heba N Deif, Amna H Faid

Abstract read
In one paragraph

Article in BMC chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  7. Bioactivity of mycosynthesized nanoparticles assists photothermal therapy of breast cancer cells.Apoptosis : an international journal on programmed cell death · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elham M MostafaDepartment of Laser Sciences and Interactions, National Institute of Laser Enhanced Science (NILES), Cairo University, Giza, Egypt.
Y BadrDepartment of Laser Sciences and Interactions, National Institute of Laser Enhanced Science (NILES), Cairo University, Giza, Egypt.
Marwa A RamadanDepartment of Laser Application in Metrology, Photochemistry, and Agriculture, National Institute for Laser Enhanced Science (NILES), Cairo University, Giza, Egypt.
Mohamed M M HashemDepartment of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Khaled Abo-El-SooudDepartment of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Heba N DeifMicrobiology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Amna H FaidDepartment of Laser Sciences and Interactions, National Institute of Laser Enhanced Science (NILES), Cairo University, Giza, Egypt. amna.hussein@cu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe antibacterial properties of silver nanoparticles (AgNPs) are extensively identified. In large quantities, they might be harmful. So many fields of nanotechnology have shown a great deal of interest in the development of an environmentally friendly, efficient method for synthesizing metal nanoparticles. Because of its antibacterial and antifungal properties toward a wide range of microbes, chitosan silver nanoparticles (AgNPs@Cs) constitute a newly developing class of bio-nanostructured hybrid materials. Furthermore, the use of photothermal therapy (PTT) has been suggested as a means of elimination of germs. These light-stimulated treatments are minimally invasive and have a few side effects. In the present work, the antibacterial effect of AgNPs at low concentrations; prepared by chemical and green methods as antimicrobial and photothermal agents in photothermal therapy; with laser irradiation were explored as combined treatment against MRSA, Pseudomonas aeruginosa, and Klebsiella pneumoniae.

methodsSilver nanoparticles were produced in two ways. First, by sodium borohydrides, second, by chitosan (as a natural eco-friendly reducing, and capping agent). The nanostructure of AgNPs and AgNPs@Cs was confirmed by UV-visible spectrometer, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIRs), and direct light scattering (DLS). The antibacterial activity of the prepared nanoparticles and the laser irradiation was tested against three bacterial species of zoonotic importance; MRSA, Pseudomonas aeruginosa, and Klebsiella pneumoniae; and was evaluated by measuring their minimum inhibitory concentrations (MIC).

resultsSilver nanoparticles produced by the two methods had spherical shapes with nearly the same particle size. The analysis of DLS showed that AgNPs were very stable with zeta potential - 28.8 mv, and 47.7 mv by chemical and chitosan synthesis, respectively. Furthermore, AgNPs@Cs showed higher antibacterial activity toward the tested bacterial species than AgNPs by chemical method. Additionally, the bacterial viability using photothermal laser therapy was reduced compared to laser and AgNPs alone. The bactericidal activities were higher when laser diode was coupled with AgNPs@Cs than by chemical reduction.

conclusionThe laser combined treatment had a higher antimicrobial effect than AgNPs alone or laser irradiation alone.

Indexed as

Antimicrobial blue laserBacteriaGreen nanotechnologyMultidrug resistanceNanomedicinePhotothermal agentsPhotothermal therapy

Identifiers

PMID39227976
PMCPMC11370005

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.