Evidence map›Paper›PMID 39228688›Full record

ArticleJBMR plus2024

Samantha R Weaver, Haydee M Torres, Katherine M Arnold, Elizabeth L Zars, Eduardo Peralta-Herrera, Earnest L Taylor, Kanglun Yu, Ezequiel Marron Fernandez de Velasco, Kevin Wickman, Meghan E McGee-Lawrence and 2 more

Abstract read
In one paragraph

Article in JBMR plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Whey Protein Phospholipid Concentrate and Its Fractions as a Diet Intervention Enhance Bone Health and Alter the Gut Microbiome in Weanling Mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Samantha R WeaverDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, United States.ORCID https://orcid.org/0000-0001-6034-214X
Haydee M TorresDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, United States.
Katherine M ArnoldDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, United States.
Elizabeth L ZarsDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, United States.
Eduardo Peralta-HerreraDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, United States.
Earnest L TaylorAltis Biosystems, Durham, NC 27709, United States.
Kanglun YuDepartment of Cellular Biology and Anatomy, Medical College of Georgia at Augusta University, Augusta, GA 30912, United States.
Ezequiel Marron Fernandez de VelascoDepartment of Pharmacology, University of Minnesota, Minneapolis, MN 55455, United States.
Kevin WickmanDepartment of Pharmacology, University of Minnesota, Minneapolis, MN 55455, United States.
Meghan E McGee-LawrenceDepartment of Cellular Biology and Anatomy, Medical College of Georgia at Augusta University, Augusta, GA 30912, United States.
Elizabeth W BradleyDepartment of Orthopedics, School of Medicine, University of Minnesota, Minneapolis, MN 55455, United States.
Jennifer J WestendorfDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, United States.

Funding

THE LEPTIN-IGF1 AXIS IN MUSCULOSKELETAL AGINGP01AG036675 · NIA · AUGUSTA UNIVERSITY · PI Meghan E. McGee-Lawrence · 2011 to 2026
$31.5M
Musculoskeletal Research Training ProgramT32AR056950 · NIAMS · MAYO CLINIC ROCHESTER · PI Jennifer J Westendorf · 2009 to 2026
$7.0M
Girk3 in bone biology and diseaseR00AR080745 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI Samantha R Weaver · 2024 to 2026
$710k
PHLPP inhibition and Osteoarthritis-Associated PainR21AR082134 · NIAMS · MAYO CLINIC ROCHESTER · PI STAFF, NATHAN P, WESTENDORF, JENNIFER J · 2023 to 2024
$380k
Girk3 in bone biology and diseaseK99AR080745 · NIAMS · MAYO CLINIC ROCHESTER · PI WEAVER, SAMANTHA R · 2023 to 2024
$210k
NIAMS NIH HHS K99 AR080745NIAMS NIH HHS R00 AR080745NIAMS NIH HHS R21 AR082134NIAMS NIH HHS T32 AR056950NIA NIH HHS P01 AG036675
6 · The paper itself

Abstract

Osteoporosis and other metabolic bone diseases are prevalent in the aging population. While bone has the capacity to regenerate throughout life, bone formation rates decline with age and contribute to reduced bone density and strength. Identifying mechanisms and pathways that increase bone accrual in adults could prevent fractures and accelerate healing. G protein-gated inwardly rectifying K

Indexed as

genetic animal modelsmicroCTosteoblastsosteoporosisWnt/β-catenin/lrps

Identifiers

PMID39228688
PMCPMC11370632

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.