Evidence map›Paper›PMID 39229117›Full record

ArticlebioRxiv : the preprint server for biology2024

Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in

Kerry McGowen, Tobias Funck, Xin Wang, Samuel Zinga, Ian D Wolf, Chidiebere C Akusobi, Claudia M Denkinger, Eric J Rubin, Mark R Sullivan

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Kerry McGowenDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.ORCID 0000-0002-8451-4070
Tobias FunckDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
Xin WangDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.ORCID 0000-0002-6930-3347
Samuel ZingaDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
Ian D WolfDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
Chidiebere C AkusobiDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
Claudia M DenkingerDepartment of Infectious Disease and Tropical Medicine, Heidelberg University Hospital & German Center of Infection Research partner site, Germany.
Eric J RubinDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
Mark R SullivanDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.ORCID 0000-0001-5765-0459

Funding

Molecular mechanisms of inherent drug resistance in non-tuberculous mycobacteriaR01AI179642 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Jeremy Michael Rock, Eric J. Rubin · 2023 to 2026
$3.1M
NIAID NIH HHS R01 AI179642
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

drug uptakeefflux pumpsintrinsic antibiotic resistancelinezolidMycobacterium abscessus

Identifiers

PMID39229117
PMCPMC11370614

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.