Evidence map›Paper›PMID 39229244›Full record

ArticlebioRxiv : the preprint server for biology2024

Glucokinase activity controls peripherally-located subpopulations of β-cells that lead islet Ca

Erli Jin, Jennifer K Briggs, Richard K P Benninger, Matthew J Merrins

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Erli JinDepartment of Medicine, Division of Endocrinology, Diabetes & Metabolism, University of Wisconsin-Madison, Madison, WI, United States.ORCID 0009-0002-9410-9738
Jennifer K BriggsDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, United States; Barbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, United States.ORCID 0000-0002-8737-2215
Richard K P BenningerDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, United States; Barbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, United States.ORCID 0000-0002-5063-6096
Matthew J MerrinsDepartment of Medicine, Division of Endocrinology, Diabetes & Metabolism, University of Wisconsin-Madison, Madison, WI, United States.ORCID 0000-0003-1599-9227

Funding

University of Colorado Anschutz Medical Campus DRCP30DK116073 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI MARIAN J REWERS · 2020 to 2026
$10.8M
Emergent Multi-Cellular Properties Regulating Pancreatic Islet FunctionR01DK106412 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Richard KP Benninger · 2015 to 2026
$4.0M
Multicellular Interactions and Dynamics of Pancreatic Islet Function in DiabetesR01DK102950 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BENNINGER, RICHARD KP · 2015 to 2024
$3.5M
Mitochondrial ADP privation: A unifying model for glucose-induced insulin secretion.R01DK127637 · NIDDK · YALE UNIVERSITY · PI KIBBEY, RICHARD G, MERRINS, MATTHEW J. · 2021 to 2025
$3.4M
Metabolic Functions of Pyruvate Kinase M2 in Pancreatic Beta CellsR01DK113103 · NIDDK · YALE UNIVERSITY · PI Matthew J. Merrins · 2017 to 2026
$3.3M
Developing ultrasound contrast agents and signal processing for structural and functional imaging in type 1 diabetesR01DK140904 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Richard KP Benninger, Mark Andrew Borden · 2024 to 2026
$1.9M
Metabolic regulation of islet hormone secretion in diabetesI01BX005113 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI MERRINS, MATTHEW J. · 2022 to 2025
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BLRD VA I01 BX005113NIDDK NIH HHS P30 DK116073NIDDK NIH HHS R01 DK102950NIDDK NIH HHS R01 DK106412NIDDK NIH HHS R01 DK113103NIDDK NIH HHS R01 DK127637NIDDK NIH HHS R01 DK140904
6 · The paper itself

Abstract

Oscillations in insulin secretion, driven by islet Ca

Identifiers

PMID39229244
PMCPMC11370332

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.