Evidence mapPaperPMID 39230790Full record

ReviewClinical and experimental medicine2024

Helicobacter pylori in oral cavity: current knowledge.

Liana Cristina Melo Carneiro Costa, Maria das Graças Carvalho, Filipa F Vale, Andreia T Marques, Lucas Trevizani Rasmussen, Tsute Chen, Melina Barros-Pinheiro

Abstract readReview
In one paragraph

Review in Clinical and experimental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Observational Study of the Association Between OralJournal of clinical medicine · 2026
    Article
  7. Diagnostics (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Article
  10. BeyondMedicina (Kaunas, Lithuania) · 2025
    Review
  11. Review
  12. Article
  13. Detection ofOpen veterinary journal · 2025
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liana Cristina Melo Carneiro Costa *Programa de Pós-graduação em Ciências da Saúde, Campus Centro-Oeste Dona Lindu, Universidade Federal de São João del-Rei (UFSJ), Divinópolis, Brazil. lianacmcosta@gmail.com.
Maria das Graças Carvalho *Departamento de Análises Clínicas e Toxicológicas da Faculdade de Farmácia da Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Filipa F Vale *BioISI - BioSystems and Integrative Sciences Institute, Faculty of Sciences, Universidade de Lisboa, Lisbon, Portugal.
Andreia T Marques *BioISI - BioSystems and Integrative Sciences Institute, Faculty of Sciences, Universidade de Lisboa, Lisbon, Portugal.
Lucas Trevizani Rasmussen *Faculty of Medicine of Marília (FAMEMA), São Paulo, Brazil.
Tsute Chen *The Forsyth Institute (Microbiology), Cambridge, MA, USA.
Melina Barros-Pinheiro *Programa de Pós-graduação em Ciências da Saúde, Campus Centro-Oeste Dona Lindu, Universidade Federal de São João del-Rei (UFSJ), Divinópolis, Brazil.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação para a Ciência e a Tecnologia UIDB/04138/2020, UIDP/04138/2020,UIDB/04046/2020, PTDC/BTM-TEC/3238/2020
6 · The paper itself

Abstract

The oral cavity may play a role as a reservoir and in the transmission and colonization of Helicobacter pylori. The route of transmission for H. pylori is not fully understood. The prevalence of this pathogen varies globally, affecting half of the world's population, predominantly in developing countries. Here, we review the prevalence of H. pylori in the oral cavity, the characteristics that facilitate its colonization and dynamics in the oral microbiome, the heterogeneity and diversity of virulence of among strains, and noninvasive techniques for H. pylori detection in oral samples. The prevalence of H. pylori in the oral cavity varies greatly, being influenced by the characteristics of the population, regions where samples are collected in the oral cavity, and variations in detection methods. Although there is no direct association between the presence of H. pylori in oral samples and stomach infection, positive cases for gastric H. pylori frequently exhibit a higher prevalence of the bacterium in the oral cavity, suggesting that the stomach may not be the sole reservoir of H. pylori. In the oral cavity, H. pylori can cause microbiome imbalance and remodeling of the oral ecosystem. Detection of H. pylori in the oral cavity by a noninvasive method may provide a more accessible diagnostic tool as well as help prevent transmission and gastric re-colonization. Further research into this bacterium in the oral cavity will offer insights into the treatment of H. pylori infection, potentially developing new clinical approaches.

Indexed as

Helicobacter InfectionsHelicobacter pyloriMouthHumansMicrobiotaPrevalenceVirulenceBiofilmHelicobacter pyloriMouthOral cavityOral microbiologyOral microbiota

Identifiers

PMID39230790
PMCPMC11374826

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.