Evidence map›Paper›PMID 39234644›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Subjective cognitive decline and cognitive change among diverse middle-aged and older Hispanic/Latino adults: Results from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).

Freddie Márquez, Wassim Tarraf, Sayaka Kuwayama, Deisha F Valencia, Ariana M Stickel, Alejandra Morlett-Paredes, Lourdes R Guerrero, Krista M Perreira, Sylvia Wassertheil-Smoller, Sara Gonzalez and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Freddie MárquezDepartment of Neurosciences, University of California San Diego, La Jolla, California, USA.ORCID 0000-0001-9916-9225
Wassim TarrafInstitute of Gerontology & Department of Healthcare Sciences, Wayne State University, Detroit, Michigan, USA.
Sayaka KuwayamaDepartment of Neurosciences, University of California San Diego, La Jolla, California, USA.
Deisha F ValenciaDepartment of Neurosciences, University of California San Diego, La Jolla, California, USA.
Ariana M StickelDepartment of Psychology, San Diego State University, San Diego, California, USA.
Alejandra Morlett-ParedesDepartment of Neurosciences, University of California San Diego, La Jolla, California, USA.
Lourdes R GuerreroDepartment of Neurosciences, University of California San Diego, La Jolla, California, USA.
Krista M PerreiraGillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Sylvia Wassertheil-SmollerDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, New York, USA.
Sara GonzalezDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, New York, USA.
Christian R SalazarInstitute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, USA.
Martha L DaviglusInstitute for Minority Health Research, University of Illinois at Chicago, College of Medicine, Chicago, Illinois, USA.
Linda C GalloDepartment of Psychology, San Diego State University, San Diego, California, USA.
Hector M GonzálezDepartment of Neurosciences, University of California San Diego, La Jolla, California, USA.

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DOUGLAS R GALASKO · 2019 to 2026
$34.9M
SDSU FUERTE: Recognition of Excellence in DEIA and Mentorship in support of Faculty SuccessU54CA267789 · NCI · SAN DIEGO STATE UNIVERSITY · PI Mark Brian Reed, Maria Luisa Zuniga de Nuncio · 2021 to 2026
$15.5M
MRI Measures of Cerebrovascular Injury and AD Atrophy in a Study of LatinosRF1AG054548 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2017 to 2017
$14.7M
Neurocognitive aging, MCI and Alzheimer's disease DNA methylation among diverse LatinosRF1AG061022 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FORNAGE, MYRIAM, GONZALEZ, HECTOR M · 2019 to 2019
$6.6M
Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)R01AG048642 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GONZALEZ, HECTOR M · 2015 to 2019
$5.7M
Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
GENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7M
UCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6M
Risk Factors for Alzheimer's Disease Among Latinos: Relationships Between Cardiovascular Disease Risk, Acculturation, Small Vessel Disease, and Alzheimer's BiomarkersK08AG075351 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ariana Stickel · 2022 to 2026
$770k
Exploring Sleep in Neurocognitive Aging and Alzheimer's Research (eSANAR)R21AG056952 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RAMOS, ALBERTO RAFAEL · 2017 to 2018
$411k
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
Albert Einstein College of Medicine N01-HC65235NCI NIH HHS U54 CA267789NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NIA NIH HHS K08 AG075351NIA NIH HHS L30 AG074401NIA NIH HHS P30 AG062429NIA NIH HHS P30AG062429NIA NIH HHS R01 AG048642NIA NIH HHS R01AG048642NIA NIH HHS R21 AG056952NIA NIH HHS R21AG056952NIA NIH HHS RF1 AG054548NIA NIH HHS RF1AG054548NIA NIH HHS RF1 AG061022NIA NIH HHS RF1AG061022NIA NIH HHS U54 CA267789NIDCD NIH HHSNIDCR NIH HHSNIDDK NIH HHSNIHNIMHD NIH HHSNINDS NIH HHS R25 NS117367Northwestern University N01-HC65236San Diego State University N01-HC65237University of Miami N01-HC65234University of North Carolina N01-HC65233
6 · The paper itself

Abstract

introductionThe potential utility of subjective cognitive decline (SCD) as an early risk marker of Alzheimer's disease and related dementias is under consideration. We examined associations between SCD and cognitive change among middle-aged and older Hispanic/Latino adults living in the United States.

methodsThe short-form Everyday Cognition Scale (ECog-12) was assessed to generate global, executive function, and memory-related SCD scores. We used survey generalized regressions to model the change in learning, memory, verbal fluency, executive function, and global cognitive performance over 7 years as a function of SCD (at Visit 2).

resultsThe mean age was 56.37 ± 8.10 years at Visit 1 (n = 6225). Higher ECog-12 was associated with greater decline in global cognitive performance (ECog-12 global: B = -0.17, standard error [SE] = 0.02; ECog-12 executive: B = -0.15, SE = 0.02; ECog-12 memory: B = -0.14, SE = 0.02, p's < 0.001). DISCUSSION: These results support the link between subjective reports of cognitive decline and objectively measured 7-year cognitive decline in community-dwelling, middle-aged, and older Hispanic/Latino adults. HIGHLIGHTS: We found that nearly two-thirds of diverse middle-aged and older Hispanics/Latinos reported cognitive concerns in a large and representative population study. Self-reported subjective experiences of cognitive decline reflect objective cognitive decline in US Hispanics/Latinos. The relationship is stronger among men compared to women. The relationship between subjective and objective changes to memory are stronger in those with cognitive concerns, and remain even in cognitively healthy individuals.

Indexed as

Cognitive DysfunctionHispanic or LatinoNeuropsychological TestsAgedExecutive FunctionFemaleHumansMaleMiddle AgedUnited StatesAlzheimer's diseasecognitive concerncognitive declinecognitive functiondementiaepidemiologyHispanicsHispanics/LatinosLatinosneuroepidemiologyneuropsychologypopulation neurosciencesubjective cognitive decline

Identifiers

PMID39234644
PMCPMC11567848

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.